Stéphanie Clément-Guinaudeau

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Based on discrete mathematical morphology, we introduce in this paper a new watershed framework which allows for segmenting spatio-temporal images, that we apply to medical image analysis. Specifically, we propose a new automated and fast procedure to segment the left ventricular myocardium in 4D (3D+t) cine-MRI sequences. Both quantitative and qualitative(More)
Based on discrete mathematical morphology, we propose a new automated and fast procedure to segment the left ventricular myocardium in 4D (3D+t) cine-MRI sequences. Thanks to the comparison with manual segmentation performed by two cardiologists, we demonstrate the accuracy of the proposed method. The relevance of the ejection fraction and myocardium mass(More)
BACKGROUND Early detection of diastolic dysfunction is crucial for patients with incipient heart failure. Although this evaluation could be performed from phase-contrast (PC) cardiovascular magnetic resonance (CMR) data, its usefulness in clinical routine is not yet established, mainly because the interpretation of such data remains mostly based on manual(More)
OBJECTIVES We analyzed, in above-average risk asymptomatic individuals, the factors determining early thoracic aorta enlargement. METHODS Ascending aortic diameter (AAD) was measured with noncontrast multidetector computed tomography in 345 participants (mean age 56 years; 78% men) without cardiovascular disease. We analyzed the associations of AAD with(More)
Background The functional impairment caused by peripheral arterial disease (PAD) is difficult to evaluate objectively and quantitatively. Current methods used to assess the efficacy of therapeutic interventions in patients with PAD are limited by variability and changes representing the placebo effect. Recently, Gadolinium-enhanced first-pass (FP) MRI has(More)
BACKGROUND Despite marked benefits in many heart failure patients, a considerable proportion of patients treated with cardiac resynchronization therapy (CRT) fail to respond appropriately. Recently, a "U-shaped" (type II) wall motion pattern identified by cardiovascular magnetic resonance (CMR) has been associated with improved CRT response compared to a(More)
Background In Cardiac Resynchronization Therapy (CRT), studies examining the importance of placing the LV pacing lead in the latest contracting segment have produced conflicting results. Some studies have shown higher response rates when the lead is placed in the latest contracting segment, while others show no relationship between lead placement and(More)
Background Cardiac resynchronization therapy (CRT) improves outcomes in many heart failure patients, yet 1 in 3 patients do not positively respond. A “U-shaped” left ventricular (LV) activation pattern (type II), suggestive of electrical conduction block, can be characterized by cardiovascular magnetic resonance (CMR) and has been associated with improved(More)
Background Many high-risk patients with severe aortic stenosis cannot undergo valve replacement surgery due to calcification of the ascending aorta. Aortic valve bypass (AVB) surgery uses a conduit and prosthetic valve placed transapically into the left ventricle to divert flow from the apex of the heart through the conduit and prosthetic valve to the(More)
Background Several echocardiographic studies demonstrated the agerelated changes in RV diastolic function. An MRI study supported these findings using SSFP sequences but to our knowledge, there is no such evaluation using PCMR images. Although blood flow PCMR imaging is less operator-dependant than echocardiography, which is strongly conditioned by the(More)