Sriram Rajagopal

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BACKGROUND We determined the effect of andrographolide and one of its novel semi-synthetic analog, DRF 3188, on the cell cycle of MCF 7 breast cancer cells. METHODS The effect of the compounds on cell cycle was determined using FACS and western blot analysis of cell cycle proteins. Hollow fibre assay was used to determine if the compounds had the same(More)
  • Seebany Datta-Barua, Walter Todd, Doug Archdeacon, Sherann Ellsworth, Dana Parga, Lynn Kaiser +57 others
  • 2008
ii I certify that I have read this dissertation and that, in my opinion, it is fully adequate in scope and quality as a dissertation for the degree of Doctor of Philosophy. I certify that I have read this dissertation and that, in my opinion, it is fully adequate in scope and quality as a dissertation for the degree of Doctor of Philosophy. I certify that I(More)
With the successful implementation of the Wide Area Augmentation System (WAAS) for the North America, there is interest in implementing similar systems in other parts of the world. The ionosphere over certain parts of the globe, notably equatorial regions and Brazil in particular, can have a far greater impact on the signals received from the satellites.(More)
The aim of the study was to develop and evaluate a self--emulsifying drug delivery system (SEDDS) formulation to improve solubility and dissolution and to enhance systemic exposure of a BCS class II anthelmetic drug, albendazole (ABZ). In the present study, solubility of ABZ was determined in various oils, surfactants and co-surfactants to identify the(More)