Srikanth Sola

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BACKGROUND Patients referred for radiofrequency pulmonary vein antral isolation undergo contrast-enhanced multidetector computed tomography (MDCT) to assess pulmonary vein and left atrial anatomy as well as transesophageal echocardiography (TEE) to detect intraatrial thrombus. We sought to determine the accuracy of MDCT to qualitatively and quantitatively(More)
BACKGROUND Despite recent advances in pharmacologic and device therapy, morbidity and mortality from heart failure (HF) remain high. Yoga combines physical and breathing exercises that may benefit patients with HF. We hypothesized that an 8-week regimen of yoga in addition to standard medical therapy would improve exercise capacity, inflammatory markers,(More)
OBJECTIVES This study examined the effect of statin therapy on vascular markers of inflammation and echocardiographic findings in patients with nonischemic forms of cardiomyopathy. BACKGROUND Despite advances in therapy, morbidity and mortality from heart failure (HF) remain high. We wished to determine whether treatment with atorvastatin affects left(More)
BACKGROUND The metabolic syndrome is associated with increased angiotensin II activity, induction of a proinflammatory and oxidative state, and endothelial dysfunction. We evaluated the ability of irbesartan, an angiotensin receptor blocker, and lipoic acid, an antioxidant, to affect endothelial function and inflammation in patients with the metabolic(More)
Our objectives were to evaluate the prognostic value of several biomarkers in patients with acute coronary syndrome (ACS) through an evaluation of the 30-day clinical outcomes. Multiple biomarkers have emerged as potentially useful in risk stratification of ACS. Specifically, markers of vascular inflammation and oxidative stress might be helpful in the(More)
OBJECTIVE Many high-risk patients with severe symptomatic aortic stenosis are not referred for surgical aortic valve replacement. Although this patient population remains ill-defined, many of these patients are now being referred for percutaneous aortic valve replacement. We sought to define the characteristics and outcomes of patients referred for(More)
BACKGROUND We wished to determine whether the addition of statins affect cardiovascular events and markers of inflammation in patients with heart failure. METHODS AND RESULTS A total of 446 patients with heart failure and ejection fraction < or =35% were followed in a prospective, nonrandomized fashion and were classified according to treatment with a(More)
OBJECTIVE Percutaneous aortic valve replacement is an emerging therapy for selected patients with severe aortic stenosis. Preoperative imaging of the aortic root facilitates sizing and deployment of the percutaneous aortic valve replacement device. We compared morphologic characteristics of the aortic root in patients with aortic stenosis versus elderly(More)
OBJECTIVES Percutaneous aortic valve insertion is an emerging treatment option for selected patients with severe aortic stenosis and may be done from a transfemoral or transapical approach. Concomitant atherosclerotic peripheral artery disease limits transfemoral access. We evaluated the potential role of multidetector computed tomography in preoperative(More)
BACKGROUND Appropriate, inappropriate, and uncertain indications for the use of cardiac computed tomography (CT) were defined by a multisociety document in 2006. We sought to compare the appropriateness of cardiac CT examinations before and after these criteria were published. METHODS We retrospectively evaluated all patients presenting for cardiac CT(More)