Srikanth Budnar

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Classical cadherin receptors mediate morphogenetic cell-cell interactions within many tissues of the body. Their biological impact often entails cooperation between cadherin adhesion and the actin cytoskeleton, but how this may occur and - even more urgently - how this leads to morphogenetic outcomes are questions that remain poorly understood. Here, we(More)
The physical properties of cells reflect how the structure and dynamics of the actomyosin cortex are coupled to the plasma membrane. In epithelia, adhesive E-cadherin clusters associate with the cell cortex to assemble the junctional actomyosin that participates in epithelial morphogenesis. E-cadherin is present not only at the apical zonula adherens (ZA),(More)
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