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Photoacoustic imaging is an emerging modality that overcomes to a great extent the resolution and depth limitations of optical imaging while maintaining relatively high-contrast. However, since many diseases will not manifest an endogenous photoacoustic contrast, it is essential to develop exogenous photoacoustic contrast agents that can target diseased(More)
Photoacoustic imaging of living subjects offers higher spatial resolution and allows deeper tissues to be imaged compared with most optical imaging techniques. As many diseases do not exhibit a natural photoacoustic contrast, especially in their early stages, it is necessary to administer a photoacoustic contrast agent. A number of contrast agents for(More)
In this paper, we demonstrate 3-D photoacoustic imaging (PAI) of light absorbing objects embedded as deep as 5 cm inside strong optically scattering phantoms using a miniaturized (4 mm × 4 mm × 500 μm), 2-D capacitive micromachined ultrasonic transducer (CMUT) array of 16 × 16 elements with a center frequency of 5.5 MHz. Two-dimensional tomographic images(More)
—A scanning acoustic and photoacoustic microscope is demonstrated. The laser illumination and ultrasound detection in the system are co-axial. Pulsed light from a tunable optical parametric oscillator (OPO) laser is delivered to the scan tank via optical fiber. Multiple acoustic transducers with center frequencies varying from 5 MHz to 25 MHz are utilized.(More)
— Capacitive micromachined ultrasonic transducers (CMUTs) overcome many limitations of existing ultrasound transducer technologies enabling new applications of ultrasound, especially for medical imaging and treatment. Some of the most important of these advancements are the ability to fabricate transducer arrays with two dimensional geometries and high(More)
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