Srey Ros

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OBJECTIVE To review the pharmacological basis of antidepressant potentiation in combination therapy and the clinical evidence for its efficacy. METHOD Literature searches were undertaken and the results reviewed. RESULTS Treatment-resistant depression is common (15-30%). Various strategies exist for dealing with resistant depression, including(More)
OBJECTIVE To review the current literature on the use of combinations of antidepressive agents. METHOD Literature searches were undertaken and reviewed on the use of combinations of antidepressants. RESULTS Data sources included surveys, analyses of prescription records, decision algorithms, clinical reports, and studies comparing the monotherapy with(More)
Antidepressant therapy in the elderly age group is frequently complicated by medical comorbidity, polypharmacy and increased sensitivity to drug effects. A nonblind, noncomparative, observational, multicentre study over 8 weeks was conducted to assess the effectiveness and tolerability of sertraline (50-200 mg/day) in 1437 elderly depressed outpatients with(More)
OBJECTIVE The present study uses the data from a large survey conducted to examine the general practice of Spanish psychiatrists on the use of antidepressant combinations in the treatment of depressive disorders. METHOD The sample was drawn from specialists and psychiatric residents practicing in Spain who were respondents to a questionnaire distributed(More)
OBJECTIVE To review the neuropharmacological basis of antidepressant combination therapy. METHOD Literature searches and other relevant material were obtained and reviewed. RESULTS The overall clinical aim of combining antidepressants is to increase the efficacy whilst minimizing the side effects. Although such prescriptions are frequently based on the(More)
OBJECTIVES The FDA approved the first human papillomavirus (HPV) vaccine in 2006. Research into parental decision-making and concerns about HPV vaccination highlights questions about parenting and parents' role in the crafting of their daughters' future sexuality. In contrast to much of this literature, we explore narratives from interviews with Cambodian(More)
OBJECTIVE To evaluate the treatment options in patients who do not respond appropriately to a single antidepressant alone. METHOD The medical literature was reviewed. RESULTS A number of strategies are available if a patient fails to respond adequately to initial antidepressant treatment, including the combination with another psychoactive drug.(More)
Stroke ranks first among nervous pathologies in Kampuchea. It's a main cause of disability and mortality in our country. We conducted a prospective study including 100 patients hospitalized in the service of general medicine at the Calmette hospital in Phnom Penh. We analyzed the principal risk factors, clinical signs, nature of stroke, complications and(More)
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