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Identification of novel universal housekeeping genes by statistical analysis of microarray data.
- S. Lee, M. Jo, Jungeun Lee, S. S. Koh, Soyoun Kim
- Biology, Medicine
- Journal of biochemistry and molecular biology
- 31 March 2007
Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase protection assays. However, even commonly… Expand
Selection of optimal internal controls for gene expression profiling of liver disease.
- Soyoun Kim, Taeuk Kim
- Biology, Medicine
- BioTechniques
- 1 September 2003
BENCHMARKS Recently developed technologies such as microarray analysis allow researchers to determine the genome-wide patterns of expressed genes. This information provides insight into complex… Expand
Gene regulations in HBV-related liver cirrhosis closely correlate with disease severity.
- S. Lee, Soyoun Kim
- Biology, Medicine
- Journal of biochemistry and molecular biology
- 30 September 2007
Liver cirrhosis (LC) is defined as comprising diffuse fibrosis and regenerating nodules of the liver. The biochemical and anatomical dysfunction in LC results from both reduced liver cell number and… Expand
Competition potency of siRNA is specified by the 5'-half sequence of the guide strand.
- J. W. Yoo, Soyoun Kim, D. Lee
- Biology, Medicine
- Biochemical and biophysical research…
- 29 February 2008
Small-interfering RNAs (siRNAs) execute specific cellular gene silencing by exploiting the endogenous RNA interference (RNAi) pathway. Therefore, excess amounts of siRNAs can saturate cellular RNAi… Expand