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Interleukin-31 and Oncostatin-M Mediate Distinct Signaling Reactions and Response Patterns in Lung Epithelial Cells*
Lung epithelial cells are primary targets of oncostatin M (OSM) and, to a lower degree, of interleukin (IL)-6 and IL-31, all members of the IL-6 cytokine family. The OSM receptor (OSMR) signalsExpand
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Regulated expression of the IL-31 receptor in bronchial and alveolar epithelial cells, pulmonary fibroblasts, and pulmonary macrophages.
Interleukin-31 (IL-31), an IL-6 cytokine family member, is proposed to play a role in animal models of airway hyperreactivity. It is produced by activated T cells and signals via a heterodimericExpand
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DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor
The related members of the interleukin 6 (IL‐6) family of cytokines, IL‐6, leukemia inhibitory factor (LIF), and oncostatin M, act as major inflammatory mediators and induce the hepatic acute phaseExpand
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Drug Interaction Assessment Strategies: Small Molecules versus Therapeutic Proteins
This chapter is not intended to give an expansive and detailed review of all ofthe methods and assays used for drug-drug interaction (DDI) assessment during small molecule drug (SMD) developmentExpand
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A Dual-Active-Bridge-Based Fully ZVS HF-Isolated Inverter With Low Decoupling Capacitance
This paper proposes a novel dual active bridge (DAB)-based high-frequency-isolated dc–ac converter topology suitable for photovoltaic microinverter applications. The circuit configuration on theExpand
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