Sotirios Spiliopoulos

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A 68-year-old man was admitted to the hospital 4 months after HeartMate II ventricular assist device implantation, because his clinical status had deteriorated and his levels of lactate dehydrogenase and free hemoglobin had increased. Transthoracic echocardiography performed at admission revealed decreased basic diastolic continuous flow velocity with a(More)
OBJECTIVES Owing to the lack of suitable allografts, the demand for long-term mechanical circulatory support in patients with biventricular end-stage heart failure is rising. Currently available Total Artificial Heart (TAH) systems consist of pump units with only limited durability, percutaneous tubes and bulky external equipment that limit the quality of(More)
OBJECTIVES Real-time monitoring of the aortic valve function and the loading state of the left ventricle (LV) during mechanical circulatory support is essential. Therefore, we developed a system that determines accurately the aortic valve closing moment based on integrals derived from the pump inlet pressure and the pump power [pressure-power area (PPA)].(More)
Beating heart surgery is still challenging and could be made safer using assisted circulation. We evaluated clinical outcome following beating heart myocardial revascularisation using the impella elect system with intracardial left ventricular (LV) and paracardial right ventricular (RV) microaxial pumps in eight patients. Clinical course was uneventful.(More)
BACKGROUND Good anatomical compatibility is an important aspect in the development of cardiovascular implants. This work analyzes the interaction of the pump unit of an electrically driven pulsatile Total Artificial Heart (TAH) and the mediastinum. For an adequate compliance, both overall dimensions and alignment of inlets and outlets must be matched. (More)
INTRODUCTION Elevated intra-abdominal pressure (IAP) has been identified as a cascade of pathophysiologic changes leading in end-organ failure due to decreasing compliance of the abdomen and the development of abdomen compartment syndrome (ACS). Spontaneous retroperitoneal hematoma (SRH) is a rare clinical entity seen almost exclusively in association with(More)
It was with great interest that we read the article by Truby et al. [1]. This is the largest single-centre trial in the post-SHOCK II-era reporting real-life experience with an aggresive strategy for the management of acute myocardial infarction complicated by cardiogenic shock. We agree that current management focusing solely on early interventional(More)
The SynCardia total artificial heart is currently used as a bridge to transplantation therapy in cases of irreversible, acute or chronic, biventricular heart failure. We describe the implementation of this technology in the context of destination therapy in a patient with an end-stage heart failure on grounds of primary amyloidosis.