Sophie Walker

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Because tau aggregation likely plays a role in a number of neurodegenerative diseases, understanding the processes that affect tau aggregation is of considerable importance. One factor that has been shown to influence the aggregation propensity is the oxidation state of the protein itself. Tau protein, which contains two naturally occurring cysteine(More)
Introduction/Group Overview The RLE Computational Biophysics Group is focused on understanding conformational changes in biomolecules that play an important role in common human diseases. The group uses an interdisciplinary approach combining computational modeling with biochemical experiments to make connections between conformational changes in(More)
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