Sophie Lemaire

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A tetrodotoxin (TTX)-sensitive fast inward Ca2+ current (ICa,TTX) was recorded at physiological Ca2+ levels (2 mM) in human single atrial cells. The whole-cell patch-clamp method and Na(+)-free solutions (20-22 degrees C) were used. ICa,TTX depended upon extracellular Ca2+. It was prominent at rather negative test potentials (maximal peak amplitude at(More)
To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population evolves according to a Moran model with weak assortative mating, strong recombination and low mutation rates. With an(More)
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