Sophie Geyl

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Good use of the submucosal space is key during endoscopic submucosal dissection (ESD). High-pressure injection of a long-lasting viscous solution using the HybridKnife water-jet system has been demonstrated to be feasible. We compared jet injection of glycerol and normal saline during pig gastric ESD and assessed its feasibility and efficiency during human(More)
INTRODUCTION Gastroparesis, or delayed gastric emptying, can be diagnosed with gastric emptying scintigraphy. Manometric studies of patients with gastroparesis show increased pyloric tone (pylorospasm). Among the recent endoscopic therapies for pylorospasm is peroral endoscopic pylorotomy (POP). In this study, we explored the effect of POP on gastric(More)
Colorectal cancer (CRC) is the most common digestive cancer in the Western world. Despite effective therapies, resistance and/or recurrence frequently occur. The present study investigated the impact of two survival pathways-neurotrophic factors (TrkB/BDNF) and autophagy-on cell fate and tumour evolution. In vitro studies were performed on two CRC cell(More)
Fig.2 Individual results for gastric emptying scintigraphy showing T1⁄2 values before and after peroral endoscopic pylorotomy (POP).. Peroral endoscopic pyloromyotomy accelerates gastric emptying in healthy pigs: proof of concept Sophie Geyl et al. Endosc Int Open 2016: DOI 10.1055/s-0042-108192 Gastroparesis, or delayed gastric emptying, can be diagnosed(More)
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