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  • Xiaoshan Zhou, Sophie Curbo, Fuqiang Li, Shuba Krishnan, Anna Karlsson
  • Medicine
  • BMC Cancer
  • 2018 (First Publication: 11 May 2018)
  • BackgroundGlutamate oxaloacetate transaminase 1 (GOT1) regulates cellular metabolism through coordinating the utilization of carbohydrates and amino acids to meet nutrient requirements. KRAS mutatedContinue Reading
  • Sophie Curbo, Marjan H Amiri, Fariba Foroogh, Magnus Johansson, Anna Karlsson
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2003 (First Publication: 1 November 2003)
  • Drosophila melanogaster cells express a multi-substrate deoxyribonucleoside kinase that phosphorylates both purine and pyrimidine deoxyribonucleosides. The subsequent phosphorylation step isContinue Reading
  • Shuba Krishnan, Xiaoshan Zhou, João A. Paredes, Raoul V. Kuiper, Sophie Curbo, Anna Karlsson
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 2013 (First Publication: 3 January 2013)
  • Background: Thymidine kinase 2 (TK2) deficiency causes severe mitochondrial DNA (mtDNA) depletion due to absence of nucleotides for mtDNA synthesis. Results: Nucleoside kinase from DrosophilaContinue Reading