Soon Joon Yoon

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We have experimentally confirmed sensitivity enhancement of a nanowire-based surface plasmon resonance (SPR) sensor structure. Gold nanowires with periods of 200 and 500 nm were fabricated, respectively, by electron-beam and interference lithography on a gold/SF10 substrate. Sensitivity enhancement was measured to be 44% compared with a conventional(More)
A nanowire-based localized surface plasmon resonance (LSPR) biosensor has been investigated to evaluate the impact of design parameters of nanowires on the excitation of localized surface plasmons (LSPs) and the sensitivity enhancement of a LSPR biosensor. The results based on rigorous coupled wave analysis and finite difference time domain method indicate(More)
Plasmonic metal nanoparticles are used in photoacoustic imaging as contrast agents because of their resonant optical absorption properties in the visible and near-IR regions. However, the nanoparticles could accumulate and result in long-term toxicity in vivo, because they are generally not biodegradable. Recently, biodegradable plasmonic gold nanoclusters,(More)
Gold nanorods (NRs) are attractive for in vivo imaging due to their high optical cross-sections and tunable absorbance. However, the feasibility of using NRs for cell tracking has not been fully explored. Here, we synthesized dye doped silica-coated NRs as multimodal contrast agents for imaging of macrophages - immune cells which play an important role in(More)
Penetration depth defines the measurable range in evanescent-wave-based sensing techniques such as surface plasmon resonance (SPR). We investigate penetration depth variation implemented with dielectric layers in a SPR sensing structure. The results show that the penetration depth can be controlled to increase or decrease depending on a specific(More)
Anisotropic gold nanorods provide a convenient combination of properties, such as tunability of plasmon resonances and strong extinction cross sections in the near-infrared to red spectral region. These properties have created significant interest in the development of antibody conjugation methods for synthesis of targeted nanorods for a number of(More)
The photothermal stability of plasmonic nanoparticles is critically important to perform reliable photoacoustic imaging and photothermal therapy. Recently, biodegradable nanoclusters composed of sub-5 nm primary gold particles and a biodegradable polymer have been reported as clinically-translatable contrast agents for photoacoustic imaging. After cellular(More)
Despite broad applications ranging from electronics to biomedical sensing and imaging, a long-standing problem of conducting polymers is the poor resistance to dedoping, which directly affects their signature electrical and optical properties. This problem is particularly significant for biomedical uses because of fast leaching of dopant ions in(More)
Elastography plays a key role in characterizing soft media such as biological tissue. Although this technology has found widespread use in both clinical diagnostics and basic science research, nearly all methods require direct physical contact with the object of interest and can even be invasive. For a number of applications, such as diagnostic measurements(More)
We have investigated the effect of surface roughness on the sensitivity of conventional and nanowire-based surface plasmon resonance (SPR) biosensors. The theoretical research was conducted using rigorous coupled-wave analysis with Gaussian surface profiles of gold films determined by atomic force microscopy. The results suggest that, when surface roughness(More)