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Thioflavin-T (ThT) is a benzothiazole dye that exhibits enhanced fluorescence upon binding to beta-amyloid (Aβ) plaques and is commonly used in the diagnosis of Alzheimer’s disease (AD). In this study, the ThT analogs were designed and synthesized, and screening was conducted for the detection of Aβ 40 fibrils in vitro. Among these compounds,(More)
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