• Publications
  • Influence
Cloud-point extraction for the determination of the free fraction of antiepileptic drugs in blood plasma and saliva.
A method for the determination of the free fraction of antiepileptic drugs in plasma and saliva was developed. The separation of free and protein-bound fractions was obtained by cloud-pointExpand
  • 40
  • 1
Interaction of carbamazepine and chlorpromazine in rabbits.
The interaction of carbamazepine and chlorpromazine in rabbits has been studied. The drugs were administrated as single oral doses (200 mg of each drug). The sequence of administration of the drugsExpand
  • 11
Interaction of carbamazepine and phenobarbital in rabbits.
The interaction of carbamazepine and phenobarbital in rabbits was investigated. The drugs were administered to the rabbit orally as a single dose. By simultaneous administration the sequence of drugsExpand
  • 2
Investigation of binding process of chlorpromazine to bovine serum albumin by means of passive and active experiments.
The association process of chlorpromazine with bovine serum albumin by both onefactoral passive and multifactoral active experiments were investigated in model systems. The dependence of absoluteExpand
  • 8
Determination of Promethazine in Blood Serum by Ion-Pair Reversed-Phase HPLC
Determination of the drug content in biological objects and investigation of drug metabolism, pharmacodynamics, and pharmacokinetics are important factors for successful therapy. This is especiallyExpand
  • 2
Determination of chlorpromazine in blood serum by ion-pair reversed-phase HPLC: Chlorpromazine pharmacokinetics in rabbits
Chlorpromazine (CP) is a strong neuroleptic of the phenothiazine group producing a sharply pronounced sedative effect, which is widely used in psychiatry [1]. The problem of chlorpromazineExpand
  • 2
[The influence of dorsal hippocampal lesion upon formation of fixated set in albino rats].
The experiments have been carried out on intact and hippocampectomized white rats. In the first stage of these experiment a two-entrance communicating chamber behind which a feeding trough was placedExpand