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We study maximum likelihood estimation for the statistical model for both directed and undirected random graph models in which the degree sequences are minimal sufficient statistics. In the undirected case, the model is known as the beta model. We derive necessary and sufficient conditions for the existence of the MLE that are based on the polytope of(More)
Several wheats (Triticum aestivum L. em Thell.) containing the short arm of chromosome 1R from rye (Secale cereale L.) translocated to the long arm of wheat chromosome 1B were examined, by in situ hybridization with a biotinylated probe, for the expression of rye rRNA genes located in the nucleolus-organizing region (NOR) present on the short arm of 1R. The(More)
We address the problem of studying the toric ideals of phylo-genetic invariants for a general group-based model on an arbitrary claw tree. We focus on the group Z2 and choose a natural recursive approach that extends to other groups. The study of the lattice associated with each phylogenetic ideal produces a list of circuits that generate the corresponding(More)
The lysosomal membrane destabilization and the metallothionein content in the digestive gland cells of mussels (Mytilus galloprovincialis Lam.), collected along the east coast of the North Adriatic (Istrian and Kvarnerine coast, Croatia), were examined over a period of four years (1996-1999). The lysosomal membrane stability, as a biomarker of general(More)
In addition to a cytoplasmic, NAD-dependent malate dehydrogenase (EC 1.1.1.37), Corynebacterium glutamicum possesses a highly active membrane-associated malate dehydrogenase (acceptor) (EC 1.1.99.16). This enzyme also takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial(More)
Little is known about the glycosylation of the isotype switched B cell receptor (BCR) in multiple myeloma, and the way it might affect receptor function. In this work IgG BCRs isolated from the individual lysates of peripheral blood lymphocytes (PBL) of 32 patients with IgG multiple myeloma and healthy controls were investigated for the expression of sialic(More)
BACKGROUND Altered glycosylation of immunoglobulin G (IgG) has been found to affect certain immunological activities of IgG and to correlate with increased inflammation in various disease states. This work deals with the changes in distribution and galactosylation of IgG subclasses present in saliva and gingival crevicular fluid (GCF) of patients with(More)
Lysosomal membrane stability, the content of neutral lipids and lipofuscin as cellular biomarkers were measured in the digestive gland of mussels, Mytilus galloprovincialis Lam., during a one year survey at selected sites along the coast of the northern Adriatic. The ability of mussels to survive in air as a general physiological response was tested at the(More)