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Background Studies of the lung function profiles of exclusive narghile smokers (ENS) are few, have some methodological limits, and present contradictory conclusions. The present study aimed to compare the plethysmographic profiles of ENS with age- and height-matched exclusive cigarette smokers (ECS). Methods Males aged 35-60 living in Sousse, Tunisia, who(More)
BACKGROUND In North-African adults, location-specific reference values for membrane diffusion capacity (D(m)) and pulmonary capillary blood volume (V(c)) were needed. OBJECTIVES To verify the applicability of previously published reference equations for D(m) and V(c) in North-African healthy adults (age >18 years) and to determine specific reference(More)
UNLABELLED Magnesium sulphate (MgSO(4)) is one of numerous treatment options available during acute asthma exacerbation. A significant, bronchodilating effect of intravenous MgSO(4) has been demonstrated in previous studies, but its inhaled use is less well-defined. OBJECTIVE To investigate the effects of inhaled MgSO(4) alone and in association with a(More)
BACKGROUND The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. OBJECTIVE To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. POPULATION AND(More)
BACKGROUND Studies on the submaximal aerobic capacity of exclusive narghile smokers (ENS) seem necessary in view of effective prevention of cardiorespiratory diseases. The goal of the study was to assess, by 6-min walk test (6MWT) data, the submaximal aerobic capacity of ENS, to identify factors influencing their 6-min walk distance (6MWD), and to compare(More)
BACKGROUND The mechanisms of smoking tobacco leading to chronic obstructive pulmonary disease (COPD) are beginning to be understood. However, conclusions about the role of blood or lung oxidative stress markers were disparate. AIMS To investigate the oxidative stress in blood or lung associated with tobacco smoke and to evaluate its effect on pulmonary(More)
After peaking between the age of 20 and 30 years, pulmonary function declines gradually with age. This decline is related to changes in respiratory dynamics (lung mechanics, gas exchange) and also to non-respiratory factors (e.g. changes in the immune system). This age-related fall in pulmonary function is not linear, for example there is no further decline(More)
INTRODUCTION There is no clear consensus as to what constitutes an obstructive ventilatory defect (OVD). According to the American Thoracic Society and European Respiratory Society, it is defined as being when the ratio of the forced expiratory volume (FEV1) and the slow expiratory vital capacity (VC) is below the lower limit of normal (LLN). According to(More)
Critical analysis of the published literature about the effects of narghile use on oral health D uring the last decades, there has been an increased trend in narghile use globally (1, 2). It has been considered as a global threat and given the status of an epidemic by public health officials (3). Several reviews were written concerning the health effects of(More)
INTRODUCTION There is no clear consensus about what constitutes reversibility of airway obstruction. European Respiratory Society (ERS): Increase in FEV1 and/or FVC>12% of their theoretical value and>0.2l. British Thoracic Society: FEV1>15% of initial value and FEV1>0.2l. Global Initiative for Chronic Obstructive Lung Disease: Increase in FEV1>12% and>0.2l.(More)