Sonia Rouatbi

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INTRODUCTION Few studies have evaluated the functional capacity of severe OSAHS. AIMS To assess their functional capacity, identify their 6-min walking-distance (6MWD) influencing factors and compare their data with those of two control-groups. METHODS Sixty (42 males) clinically consecutive stable patients with severe OSAHS under CPAP were included.(More)
BACKGROUND The lung is subject to many physiological changes during life. The aim of this study was to identify factors that influence gas transfer, which depends on membrane diffusion (Dm) and pulmonary capillary blood volume (Vc). METHODS Dm and Vc measurements were performed at rest in 135 healthy patients divided into three groups according to age and(More)
UNLABELLED Magnesium sulphate (MgSO(4)) is one of numerous treatment options available during acute asthma exacerbation. A significant, bronchodilating effect of intravenous MgSO(4) has been demonstrated in previous studies, but its inhaled use is less well-defined. OBJECTIVE To investigate the effects of inhaled MgSO(4) alone and in association with a(More)
BACKGROUND The applicability of the recent multi-ethnic reference equations derived by the ERS Global Lung Initiative (ERS/GLI) in interpreting spirometry data in North African adult subjects has not been studied. OBJECTIVE To ascertain how well the recent ERS/GLI reference equations fit contemporary adult Tunisian spirometric data. POPULATION AND(More)
BACKGROUND The mechanisms of smoking tobacco leading to chronic obstructive pulmonary disease (COPD) are beginning to be understood. However, conclusions about the role of blood or lung oxidative stress markers were disparate. AIMS To investigate the oxidative stress in blood or lung associated with tobacco smoke and to evaluate its effect on pulmonary(More)
After peaking between the age of 20 and 30 years, pulmonary function declines gradually with age. This decline is related to changes in respiratory dynamics (lung mechanics, gas exchange) and also to non-respiratory factors (e.g. changes in the immune system). This age-related fall in pulmonary function is not linear, for example there is no further decline(More)
Background Studies of the lung function profiles of exclusive narghile smokers (ENS) are few, have some methodological limits, and present contradictory conclusions. The present study aimed to compare the plethysmographic profiles of ENS with age- and height-matched exclusive cigarette smokers (ECS). Methods Males aged 35-60 living in Sousse, Tunisia, who(More)
BACKGROUND In North-African adults, location-specific reference values for membrane diffusion capacity (D(m)) and pulmonary capillary blood volume (V(c)) were needed. OBJECTIVES To verify the applicability of previously published reference equations for D(m) and V(c) in North-African healthy adults (age >18 years) and to determine specific reference(More)
BACKGROUND Studies on the submaximal aerobic capacity of exclusive narghile smokers (ENS) seem necessary in view of effective prevention of cardiorespiratory diseases. The goal of the study was to assess, by 6-min walk test (6MWT) data, the submaximal aerobic capacity of ENS, to identify factors influencing their 6-min walk distance (6MWD), and to compare(More)
The study was conducted to characterize the action of NaF, which had relaxing property in carbachol precontracted isolated bovine bronchus, on airway responsiveness challenged by acetylcholine receptor agonists in rats and asthmatic humans. Tracheal flow rate and airway resistance were measured in anaesthetized rats. NaF was delivered either before(More)