Sonia R Skamene

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This study aims at developing a joint FDG-PET and MRI texture-based model for the early evaluation of lung metastasis risk in soft-tissue sarcomas (STSs). We investigate if the creation of new composite textures from the combination of FDG-PET and MR imaging information could better identify aggressive tumours. Towards this goal, a cohort of 51 patients(More)
OBJECTIVE The purpose of this study was to determine if there is an association between necrosis as identified on staging (18)F-FDG PET/CT and overall survival (OS) and progression-free survival (PFS) in patients with sarcoma. MATERIALS AND METHODS Sixty-six patients with newly diagnosed limb and girdle sarcoma underwent PET/CT at our institution between(More)
OBJECTIVE The objective of our study was to determine whether there is a statistically significant correlation between metabolic activity of osseous and soft-tissue sarcomas as measured by the maximum standardized uptake value (SUV(max)) on (18)F-FDG PET/CT and histopathologic characteristics such as mitotic counts, the presence of necrosis, and the(More)
OBJECTIVE To explore the relationship between metabolic activity and outcome in patients with extremity sarcomas. METHODS Between June 2004 and December 2011, 120 patients with newly diagnosed limb and girdle sarcomas underwent FDG-PET/CT for disease staging prior to curative intent treatment. The maximum standardized uptake value (SUV(max)) was measured(More)
PURPOSE The current recommended practice for pediatric patients with metastatic rhabdomyosarcoma includes full-dose radiotherapy to each metastatic site. We wished to question this practice, which can cause side-effects and is often logistically challenging, by studying the pattern of failure in our pediatric and teenage patient population. METHODS AND(More)
PURPOSE To investigate the potential of joint FDG-PET/MR imaging features for the prediction of lung metastases at diagnosis of soft-tissue sarcomas (STS). METHODS A cohort of 35 patients with histologically proven STS was used in this study. All patients underwent pre-treatment FDG-PET and MR scans that comprised T1 and T2-fat suppression weighted (T2FS)(More)
BACKGROUND CONTEXT Predicting survival outcomes after radiation therapy alone for metastatic disease of the spine is a challenging task that is important to guiding treatment decisions (e.g., determining dose fractionation and intensity). The New England Spinal Metastasis Score (NESMS) was recently introduced and validated in independent cohorts as a tool(More)
PURPOSE To investigate the combination of PET/MR image features for the early prediction of tumor metastases to the lungs in soft-tissue sarcoma (STS) cancer. METHODS A dataset of 24 patients with histologically proven STS was used in this study. All patients underwent pre-treatment FDG-PET and MR scans, which comprised of T1 and T2-fat suppression(More)
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