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- Yasuhiro Funahashi, Sonia L. Hernandez, +13 authors Jan Kitajewski
- Cancer research
- 2008
Notch signaling is required for vascular development and tumor angiogenesis. Although inhibition of the Notch ligand Delta-like 4 can restrict tumor growth and disrupt neovasculature, the effect of… (More)
- Sonia L. Hernandez, Debarshi Banerjee, +9 authors Darrell J. Yamashiro
- Vascular cell
- 2013
BACKGROUND
Anti-angiogenesis is a validated strategy to treat cancer, with efficacy in controlling both primary tumor growth and metastasis. The role of the Notch family of proteins in tumor… (More)
- Shashank R. Sirsi, Sonia L. Hernandez, +7 authors Mark A. Borden
- Journal of controlled release : official journal…
- 2012
Microbubble ultrasound contrast agents are being developed as image-guided gene carriers for targeted delivery in vivo. In this study, novel polyplex-microbubbles were synthesized, characterized and… (More)
- Nibal Zaghloul, Sonia L. Hernandez, +6 authors Darrell J. Yamashiro
- International journal of oncology
- 2009
Most children with neuroblastoma presenting after infancy have metastatic, chemoresistant disease. Amplification of the MYCN proto-oncogene is a significant marker of these poor-prognosis… (More)
- Shashank R. Sirsi, Molly Flexman, +12 authors Mark A. Borden
- Ultrasound in medicine & biology
- 2012
Agents targeting vascular endothelial growth factor (VEGF) have been validated as cancer therapeutics, yet efficacy can differ widely between tumor types and individual patients. In addition, such… (More)
- Sonia L. Hernandez, Jennifer H. Gong, +4 authors George L King
- Diabetes care
- 2014
OBJECTIVE
We characterized and correlated endothelial progenitor cells (EPCs) and circulating progenitor cells (CPCs) with lack of vascular complications in the Joslin Medalist Study in patients with… (More)
- Debarshi Banerjee, Sonia L. Hernandez, +10 authors Darrell J. Yamashiro
- Cancer research
- 2015
The Notch pathway plays multiple key roles in tumorigenesis, and its signaling components have therefore aroused great interest as targets for emerging therapies. Here, we show that inhibition of… (More)
- Ann M. Defnet, Naina Bagrodia, Sonia L. Hernandez, Natalie Gwilliam, Jessica J. Kandel
- Pediatric Surgery International
- 2016
Multimodal treatment of lymphatic malformations continues to expand as new information about the biology and genetics of these lesions is discovered, along with knowledge gained from clinical… (More)
- Sonia L. Hernandez, PhD Annette K. Taylor MS, +10 authors Jessica J. Kandel
- Angiogenesis
- 2018
Staphylococcus aureus infection is one of the leading causes of morbidity in hospitalized patients in the United States, an effect compounded by increasing antibiotic resistance. The secreted agent… (More)
- Ashish Jani, Fauzia Shaikh, +8 authors E P Connolly
- International journal of radiation oncology…
- 2016
PURPOSE
To characterize the effects of high-dose radiation therapy (HDRT) on neuroblastoma tumor vasculature, including the endothelial cell (EC)-pericyte interaction as a potential target for… (More)