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Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry.
It has been found that carbon nanotubes can transfer energy to the analyte under laser irradiation, which makes analytes well desorbed/ionized, and the interference of intrinsic matrix ions can be eliminated. Expand
Using oxidized carbon nanotubes as matrix for analysis of small molecules by MALDI-TOF MS
  • C. Pan, Songyun Xu, +6 authors B. Guo
  • Chemistry, Medicine
  • Journal of the American Society for Mass…
  • 1 June 2005
The matrix of oxidized carbon nanotubes tested as a matrix for analysis of small molecules by matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) has great potential for monitoring reactions and for product quality control. Expand
Zirconium phosphonate-modified porous silicon for highly specific capture of phosphopeptides and MALDI-TOF MS analysis.
The prepared ZrP-pSi wafer has been successfully applied for the enrichment of phosphopeptides from the tryptic digest of standard phosphoproteins beta- casein and alpha-casein and the excellent selectivity of this approach was demonstrated. Expand
Fe3+ immobilized metal affinity chromatography with silica monolithic capillary column for phosphoproteome analysis
It was demonstrated that Fe3+‐IDA silica monolithic IMAC capillary column could specifically capture the phosphopeptides from tryptic digest of α‐casein with analysis by MALDI‐TOF MS. Expand
Highly specific enrichment of phosphopeptides by zirconium dioxide nanoparticles for phosphoproteome analysis
The high specificity of this approach was demonstrated by the isolation of phosphopeptides from the digests of model phosphoproteins, and Superior selectivity of ZrO2 nanoparticles for the enrichment of phosphorylated peptides than that of conventional immobilized metal affinity chromatography was observed. Expand
Characterization of small-molecule–biomacromolecule interactions: From simple to complex
The interactions between small molecules and biomacromolecules constitute one of the most important parts of interconnected biological networks. To understand the recognition mechanisms of theseExpand
Enrichment of peptides from plasma for peptidome analysis using multiwalled carbon nanotubes.
A novel peptidome analysis approach using multiwalled carbon nanotubes (MWCNTs) as an alternative adsorbent to capture endogenous peptides from human plasma could hold promise of routine plasma peptidomes analysis. Expand
Iminodiacetic acid derivatized porous silicon as a matrix support for sample pretreatment and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis.
Iminodiacetic acid (IDA)-1,2-epoxy-9-decene has been synthesized and covalently linked to the surface of porous silicon wafer through a photochemical reaction, allowing the removal of contaminants prior to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) by simply washing the porous silicon surface. Expand
Retention Time Mass-charge Ratio Pairs for Label-free Differential Analysis of Peptides
Abstract A simple LC-MS based methodology is presented that allows relative changes in the abundance of peptides in highly complex mixtures to be determined. The proposed method involves signalExpand
Recent developments in methods and technology for analysis of biological samples by MALDI-TOF-MS
Recent developments in matrix additives, new matrices, and sample-pretreatment methods using off-prob or on-probe techniques or nanomaterials for MALDI-TOF-MS analysis of biological samples are summarized. Expand