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An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)].
  • Songping Liang
  • Biology, Medicine
  • Toxicon : official journal of the International…
  • 1 April 2004
The bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)] is one of the most venomous spiders in China. The venom of this spider contains a mixture of compounds with different types ofExpand
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Proteome and peptidome profiling of spider venoms
  • Songping Liang
  • Biology, Medicine
  • Expert review of proteomics
  • 1 October 2008
Spider venoms are an important source of novel molecules with different pharmacological properties. Recent technological developments of proteomics, especially mass spectrometry, have greatlyExpand
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A novel tarantula toxin stabilizes the deactivated voltage sensor of bacterial sodium channel
  • C. Tang, X. Zhou, +7 authors Z. Liu
  • Medicine, Chemistry
  • FASEB journal : official publication of the…
  • 11 April 2017
Voltage‐gated sodium channels (NaVs) are activated by transiting the voltage sensor from the deactivated to the activated state. The crystal structures of several bacterial NaVs have captured theExpand
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Spider Toxin Peptide Lycosin-I Functionalized Gold Nanoparticles for in vivo Tumor Targeting and Therapy
Cell penetrating peptides (CPPs) are commonly utilized for intracellular delivery of functional materials to circumvent biomembrane barrier. However, further application of CPPs is hindered byExpand
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Proteomic Comparison of Two-Dimensional Gel Electrophoresis Profiles from Human Lung Squamous Carcinoma and Normal Bronchial Epithelial Tissues
Differential proteome profiles of human lung squamous carcinoma tissue compared to paired tumor-adjacent normal bronchial epithelial tissue were established and analyzed by means of immobilized pHExpand
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Protein compositional analysis of the eggs of black widow spider (Latrodectus tredecimguttatus): implications for the understanding of egg toxicity.
Previous work found that high-molecular-weight fractions in the egg extract of Latrodectus tredecimguttatus exhibited strong toxicities. For investigating the possible relationship of proteins in theExpand
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Characterization of a Novel BmαTX47 Toxin Modulating Sodium Channels: The Crucial Role of Expression Vectors in Toxin Pharmacological Activity
Long-chain scorpion toxins with four disulfide bridges exhibit various pharmacological features towards the different voltage-gated sodium channel subtypes. However, the toxin production stillExpand
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A survey of the venom of the spider Lycosa vittata by biochemical, pharmacological and transcriptomic analyses.
Lycosa vittata, mainly distributed in the southwest of China, is a medium-sized and venomous spider, whose venom remains unexplored so far. This study aims to present an overview of the venom. ItExpand
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Quantifying the Distribution of the Stoichiometric Composition of Anticancer Peptide Lycosin-I on the Lipid Membrane with Single Molecule Spectroscopy.
Lycosin-I, a peptide toxin derived from spider venom, has been demonstrated to be a promising candidate for the inhibition of tumor cell growth in vitro and in vivo by interacting with andExpand
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Peptide‐rich venom from the spider Heteropoda venatoria potently inhibits insect voltage‐gated sodium channels
ABSTRACT Heteropoda venatoria is a venomous spider species distributed worldwide and has a characteristic habit of feeding on insects. Reverse‐phase high‐performance liquid chromatography andExpand
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