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Changes in gene expression levels determine differentiation of tissues involved in development and are associated with functional decline in aging. Although development is tightly regulated, the transition between development and aging, as well as regulation of post-developmental changes, are not well understood. Here, we measured messenger RNA (mRNA),(More)
BACKGROUND Microarrays revolutionized biological research by enabling gene expression comparisons on a transcriptome-wide scale. Microarrays, however, do not estimate absolute expression level accurately. At present, high throughput sequencing is emerging as an alternative methodology for transcriptome studies. Although free of many limitations imposed by(More)
Over the course of ontogenesis, the human brain and human cognitive abilities develop in parallel, resulting in a phenotype strikingly distinct from that of other primates. Here, we used microarrays and RNA-sequencing to examine human-specific gene expression changes taking place during postnatal brain development in the prefrontal cortex and cerebellum of(More)
— In the vision of the Internet of Things (IoT), an increasing number of embedded devices of all sorts (e.g., sensors, mobile phones, cameras, smart meters, smart cars, traffic lights, smart home appliances, etc.) are now capable of communicating and sharing data over the Internet. Although the concept of using embedded systems to control devices, tools and(More)
As the world's second largest economy, China has experienced severe haze pollution, with fine particulate matter (PM) recently reaching unprecedentedly high levels across many cities, and an understanding of the PM formation mechanism is critical in the development of efficient mediation policies to minimize its regional to global impacts. We demonstrate a(More)
Hadoop is seriously limited by its MapReduce scheduler which does not scale well in heterogeneous environment. Heterogenous environment is characterized by various devices which vary greatly with respect to the capacities of computation and communication, architectures, memorizes and power. As an important extension of Hadoop, LATE MapReduce scheduling(More)
MicroRNA-mediated gene regulation is important in many physiological processes. Here we explore the roles of a microRNA, miR-941, in human evolution. We find that miR-941 emerged de novo in the human lineage, between six and one million years ago, from an evolutionarily volatile tandem repeat sequence. Its copy-number remains polymorphic in humans and shows(More)
This paper presents a novel patchwork-based embedding and decoding scheme for digital audio watermarking. At the embedding stage, an audio segment is divided into two subsegments and the discrete cosine transform (DCT) coefficients of the subsegments are computed. The DCT coefficients related to a specified frequency region are then partitioned into a(More)
After a decade of extensive research on application-specific wireless sensor networks (WSNs), the recent development of information and communication technologies make it practical to realize new WSNs paradigm known as software-defined sensor networks (SDSNs). SDSNs are able to adapt to various application requirements and to fully explore the(More)