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Changes in gene expression levels determine differentiation of tissues involved in development and are associated with functional decline in aging. Although development is tightly regulated, the transition between development and aging, as well as regulation of post-developmental changes, are not well understood. Here, we measured messenger RNA (mRNA),(More)
Hadoop is seriously limited by its MapReduce scheduler which does not scale well in heterogeneous environment. Heterogenous environment is characterized by various devices which vary greatly with respect to the capacities of computation and communication, architectures, memorizes and power. As an important extension of Hadoop, LATE MapReduce scheduling(More)
In development, timing is of the utmost importance, and the timing of developmental processes often changes as organisms evolve. In human evolution, developmental retardation, or neoteny, has been proposed as a possible mechanism that contributed to the rise of many human-specific features, including an increase in brain size and the emergence of(More)
Over the course of ontogenesis, the human brain and human cognitive abilities develop in parallel, resulting in a phenotype strikingly distinct from that of other primates. Here, we used microarrays and RNA-sequencing to examine human-specific gene expression changes taking place during postnatal brain development in the prefrontal cortex and cerebellum of(More)
In the vision of the Internet of Things (IoT), an increasing number of embedded devices of all sorts (e.g., sensors, mobile phones, cameras, smart meters, smart cars, traffic lights, smart home appliances, etc.) are now capable of communicating and sharing data over the Internet. Although the concept of using embedded systems to control devices, tools and(More)
Among other factors, changes in gene expression on the human evolutionary lineage have been suggested to play an important role in the establishment of human-specific phenotypes. However, the molecular mechanisms underlying these expression changes are largely unknown. Here, we have explored the role of microRNA (miRNA) in the regulation of gene expression(More)
Distributed Denial of Service (DDoS) attack is a critical threat to the Internet, and botnets are usually the engines behind them. Sophisticated botmasters attempt to disable detectors by mimicking the traffic patterns of flash crowds. This poses a critical challenge to those who defend against DDoS attacks. In our deep study of the size and organization of(More)
The effect of ethanol exposure upon several parameters relating to oxidative stress has been examined in brain and liver. A single administration of either acetaldehyde or ethanol was able to enhance rates of generation of reactive oxygen species in liver but this effect was not apparent in the cerebral cortex. Glutamine synthetase is especially sensitive(More)
We consider the problem of maximizing the network lifetime in WANETs (wireless ad hoc networks) with limited energy resources using omnidirectional or directional antennas. Unlike most solutions that use a centralized multicast algorithm, we use graph-theoretic approach to solve the problem in a distributed manner. After providing a globally optimal(More)
[1] In this study, ultraviolet TOMS (Total Ozone Mapping Spectrometer) satellite data for SO2 are reevaluated for the first 15 days following the 15 June 1991 Pinatubo eruption to reflect new data retrieval and reduction methods. Infrared satellite SO2 data from the TOVS/HIRS/2 (TIROS (Television Infrared Observation Satellite) Optical Vertical Sounder/High(More)