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Mental imagery generation is essential in the retrieval and storage of knowledge. Previous studies have indicated that the holistic properties of mental imagery generation can be evaluated more easily than the partial properties. However, the relationship between partial and holistic mental imagery generations has not been clearly demonstrated. To address(More)
Surface-enhanced Raman scattering (SERS) is a powerful spectroscopy technique that can provide non-destructive and ultra-sensitive characterization down to single molecular level, comparable to single-molecule fluorescence spectroscopy. However, generally substrates based on metals such as Ag, Au and Cu, either with roughened surfaces or in the form of(More)
IMPORTANCE Heart failure (HF) guidelines recognize that a subset of patients with HF and preserved left ventricular ejection fraction (LVEF) previously had reduced LVEF but experienced improvement or recovery in LVEF. However, data on these patients are limited. OBJECTIVE To investigate the characteristics and outcomes of adult outpatients with HF and(More)
Surface-enhanced Raman scattering (SERS) is a powerful fingerprint vibrational spectroscopy with a single-molecule detection limit, but its applications are generally restricted to 'free-electron-like' metal substrates such as Au, Ag and Cu nanostructures. We have invented a shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS) technique, using(More)
BACKGROUND/OBJECTIVES Cystatin-C and beta-2-microglobulin may be superior to serum creatinine, blood urea nitrogen (BUN), or estimated glomerular filtration rate (eGFR) in patients hospitalized with heart failure (HF). We compared these renal markers in ambulatory HF patients. METHODS We prospectively evaluated the association of baseline renal markers(More)
BACKGROUND Pulmonary hypertension (PH) in patients with heart failure (HF) is associated with worse outcomes and is rapidly being recognized as a therapeutic target. To facilitate pragmatic research efforts, data regarding the prognostic importance of noninvasively assessed pulmonary artery systolic pressure (PASP) in stable ambulatory patients with HF are(More)
Efficacy of the conjugate anti-AFP-F(ab)'2 with adriamycin, anti-AFP-F(ab)'2-adr, against transplantable tumors was studied in mice. The results showed that LD50 of anti-AFP-F(ab)'2-adr in mice was 7.43 mg/kg and that anti-AFP-F(ab)'2-adr in a dose of 1/10-1/5 LD50 could inhibit the growth of transplanted hepatocellular carcinoma. In addition,(More)
BACKGROUND Impaired spirometric parameters have been reported in patients with stage C heart failure and portend worse outcomes in these patients. The impact of spirometric parameters on outcomes in patients with stage D heart failure listed for heart transplantation is unknown. METHODS We collected data on consecutive subjects listed for heart(More)
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