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Meditation programs for psychological stress and well-being: a systematic review and meta-analysis.
TLDR
Clinicians should be aware that meditation programs can result in small to moderate reductions of multiple negative dimensions of psychological stress and should be prepared to talk with their patients about the role that a meditation program could have in addressing psychological stress. Expand
Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis.
TLDR
The findings indicate that favorable levels of adherence, much of which was assessed via patient self-report, can be achieved in sub-Saharan African settings and that adherence remains a concern in North America. Expand
Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators
TLDR
Important barriers to adherence are consistent across multiple settings and countries, and Clinicians should use this information to engage in open discussion with patients to promote adherence and identify barriers and facilitators within their own populations. Expand
Comparative Effectiveness and Safety of Medications for Type 2 Diabetes: An Update Including New Drugs and 2-Drug Combinations
TLDR
Evidence supports metformin as a first-line agent to treat type 2 diabetes and most 2-drug combinations similarly reduce hemoglobin A(1c) levels, but some increased risk for hypoglycemia and other adverse events. Expand
Adherence to Antiretroviral Therapy in Sub-Saharan Africa and North America
Montessori et al,52 2000 0.57 (0.54-0.60) Robertson et al,51 2006 0.68 (0.50-0.82) Temoshok and Wald,5
Risk of Clostridium difficile Infection With Acid Suppressing Drugs and Antibiotics: Meta-Analysis
TLDR
Despite the substantial statistical and clinical heterogeneity, the findings indicate a probable association between PPI use and incident and recurrent CDI, which is further increased by concomitant use of antibiotics and PPI, whereas H2RAs may be less harmful. Expand
Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.
TLDR
Inhaled anticholinergics are associated with a significantly increased risk of cardiovascular death, MI, or stroke among patients with COPD. Expand
Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study.
TLDR
Treatment with the GLP-1-based therapies sitagliptin and exenatide was associated with increased odds of hospitalization for acute pancreatitis in US adults with type 2 diabetes mellitus. Expand
Wernicke encephalopathy after obesity surgery: a systematic review.
TLDR
Wernicke encephalopathy after bariatric surgery usually occurs between 4 and 12 weeks postoperatively, especially in young women with vomiting, and atypical neurologic features are common. Expand
Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis.
TLDR
Among patients with impaired glucose tolerance or type 2 diabetes, rosiglitazone use for at least 12 months is associated with a significantly increased risk of myocardial infarction and heart failure, without a significantlyIncreased risk of cardiovascular mortality. Expand
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