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We have examined the effect of Delta1-tetrahydrocannabinol (delat1-THC) and 12 of its derivatives on the uptake of 3H-labeled norepinephrine (NE), dopamine (DA), serotonin (5-HT) gamma-aminobutyric acid (GABA) into synaptosomes in homogenates of various regions of rat brain. Delta1-THC inhibits the accumulation of NE and 5-HT into hypothalamic preparations(More)
PURPOSE Vitreoretinal disorders are frequently characterized by increased vitreous levels of cellular mediators, including cytokines, chemokines, and growth factors. The study was conducted to investigate whether multiplex bead analysis could identify disease-specific profiles of these mediators in a variety of vitreoretinal diseases. METHODS Levels of 19(More)
The article presents the experiments carried out as part of the participation in the main task of QA4MRE@CLEF 2011. We have submitted total five unique runs in the main task: two runs from systems based on Answer Validation (AV) machine reading techniques, one run from systems based on Question Answering (QA) techniques while the last two runs are hybrid(More)
The article presents the experiments carried out as part of the participation in the pilot task of QA4MRE@CLEF 2013. In the developed system, we have first generated answer pattern by combining the question and each answer option to form the Hypothesis (H). Stop words and interrogative word are removed from each H and query words are identified to retrieve(More)
PURPOSE Vitreoretinal disorders lack specific biomarkers that define either disease type or response to treatment. We have used NMR-based metabolomic analysis of human vitreous humor to assess the applicability of this approach to the study of ocular disease. METHODS Vitreous samples from patients with a range of vitreoretinal disorders were subjected to(More)
The rapid expansion of blog and electronic data in Web 2.0 is abounding and thus it is becoming important to identify the author " s profile also. The problems of automatic identification of author " s gender and age based on linguistic and stylistic pattern have been a subject of increasingly research interest in the recent years. The research(More)
The effects of streptozotocin-induced diabetes on the retinal dopaminergic system have been examined in Long-Evans (pigmented) rats. Tyrosine hydroxylase activity was significantly decreased while dopamine-stimulated adenylate cyclase was increased in 2-month-diabetic rats. The observed increase in dopamine-stimulated adenylate cyclase activity in diabetic(More)
The article presents the experiments carried out as part of the participation in the main task of QA4MRE@CLEF 2012. In the developed system, we first combine the question and each answer option to form the Hypothesis (H). Stop words are removed from each H and query words are identified to retrieve the most relevant sentences from the associated document(More)