Somayeh Zargooshnia

Learn More
Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) can lead to spatial memory impairments and hippocampal cell death. Numerous evidence indicates that the antioxidant N-acetylcysteine (NAC) exerts protective effects in the brain. The present study evaluates the effects of NAC on MDMA–induced neurotoxicity. Methods: We intraperitoneally injected 28 adult(More)
Alzheimer's disease (AD) is a neurodegenerative disorder and most common form of dementia that leads to memory impairment. In the present study we have examined the protective effects of Borago officinalis (borage) extract on Amyloid β (A β)-Induced memory impairment. Wistar male rats received intrahippocampal (IHP) injection of the A β (25-35) and borage(More)
Alzheimer’s disease (AD) begins with impairment in synaptic functions before developing into later neurodegeneration and neural loss. In the present study we have examined the protective effects of Borago Officinalis (borage) extract on amyloid β (Aβ)—Induced long term potentiation (LTP) disruption in hippocampal dentate gyrus (DG). Wistar male rats(More)
Erratum to: The protective effect of Borago Officinalis extract on amyloid β (25–35)-induced long term potentiation disruption in the dentate gyrus of male rats The original version of this article unfortunately contained a mistake. Schematic view of hippocampus that illustrates the place of stimulating and recording electrodes is from a published article(More)
Background: Alzheimer's disease (AD) is the most common form of dementia that leads to neurotoxicity. Amyloid β-peptide (Aβ) has a pivotal role in the pathogenesis of AD. Objectives: Given the contradictory results of Aβ (25-35) on the memory, in the present study we have examined the effect of Aβ-induced memory impairment. Materials and Methods: Wistar(More)
  • 1