Soma Murthy

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Lysine, an essential amino acid is catabolized in brain through only the pipecolic acid pathway. During the formation of pipecolic acid, alpha-deamination of lysine, and the formation of the alpha-keto acid as well as its cyclized product are pre-requisites. The enzyme mediated alpha-deamination of L-lysine and the formation of the alpha-keto acid and the(More)
Lysine, an essential amino acid is catabolized in brain through only the pipecolic acid pathway. During the formation of pipecolic acid, α-deamination of lysine, and the formation of the α-keto acid as well as its cyclized product are pre-requisites. The enzyme mediated α-deamination of L-lysine and the formation of the α-keto acid and the cyclized product(More)
Despite its remarkable barrier function, the skin remains an attractive site for systemic drug delivery given its easy accessibility, large surface area and the possibility to bypass the gastrointestinal tract and the liver and so modify drug absorption kinetics. The pioneering work of Scheuplein, Higuchi and others in the 1960s helped to explain the(More)
OBJECTIVE To provide commentary and reviews and brief discussions in controversial or innovative recent advances in neonatal pharmacotherapy. To discuss cutting edge drug delivery systems that may become useful in neonatal drug delivery in the future. DATA SOURCES Articles were identified through searches of MEDLINE (1990-October 2005), key articles in(More)
While the networks of different Telecommunications Administrations forming a global network are interconnected, their Network Management Systems (NMSs) are isolated from each other. As a result, various network management functions (e.g., configuration, fault management) necessary for managing the network resources common to the administrations require(More)
BACKGROUND Woodfordia fruticosa (L.) Kurz., known as Dhataki, is an important medicinal plant used in Ayurveda. Recent studies on leaf showed that it contains important chemical constituents responsible for biological activities. The ethnic folk from India and Nepal are using the leaf to treat ulcers, rheumatism, fever, hemoptysis and as a disinfectant. It(More)
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