Soma Bhattacharyya

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Lysis of autologous tumor cells (ATC) mediated by the tumor associated macrophages (TAM) was studied by 4 h 51Cr-release assay at different days of growth of a transplantable ascites tumor, S-180, inoculated in adult male Swiss mice. The ATC were coated with serum of tumor bearing mice. On day 3 after tumor inoculation the TAM mediated a remarkable lysis of(More)
Two haploid strains of Saccharomyces cerevisiae viz. MATalpha and MATa were grown in glucose and trehalose medium and growth patterns were compared. Both strains show similar growth, except for an extended lag phase in trehalose grown cells. In both trehalose grown strains increase in activities of both extracellular trehalase activities and simultaneous(More)
The phagocytic activity of the tumor associate macrophages isolated at different days of the growth of a murine transplantable ascites tumor was assessed by measuring the engulfment of Na2 51CrO4 labeled antibody coated sheep erythrocytes. Binding of the targets by the macrophages was also assessed. It was observed that, excepting the day 3, till day 7 of(More)
A number of mono- and oligosaccharides are known to inhibit direct contact mediated cytotoxicity of natural killer cells, cytotoxic T lymphocytes and macrophages. In antibody dependent cell mediated cytotoxicity (ADCC), where antibody molecules mediate target recognition, binding and lysis, the role of cell surface carbohydrates is not clearly defined. In(More)
Lectin dependent cell mediated cytotoxicity (LDCC) to autologous tumor cells (ATC) by the tumor associated macrophages (TAM) was studied by 4 h 51Cr release assays at early and late stages of growth of a murine transplantable ascites tumor, S-180, in presence of different concentrations of wheat germ agglutinin (WGA) and Concanavalin A (Con A). Induction of(More)
Effect of a potent methylation inhibitor oxidized adenosine (Adox), and a universal methyl group donor S-adenosyl-L-methionine (AdoMet) on trehalose metabolism was studied in two haploids of S. cerevisiae of mating types MATalpha, met3 (6460 -8D) and MATa, leu2, ura3, his4 (8534 -10A). Trehalose level decreased in presence of Adox in both strains. Both(More)
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