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  • Stefan A Laufer, Gabriele M Ahrens, Solveigh Cornelia Karcher, Jörg S Hering, Raimund Niess
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1 December 2006
  • The pathogenesis of chronic inflammatory diseases is promoted by various pro-inflammatory cytokines. p38 MAP kinase seems to be a valid target as it controls proinflammatory cytokine levels on bothContinue Reading
  • Solveigh Cornelia Karcher, Stefan A Laufer
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 26 March 2009
  • We recently described a promising novel class of p38 mitogen activated protein (MAP()) kinase inhibitors with dibenzepinone-scaffolds. To optimize their physicochemical properties, characterized byContinue Reading
    s / Neuroscience Research 68S (2010) e223–e334 e233 found that the presynaptic level of the BMP-induced Mad phosphorylation was significantly reduced in trol mutants, showing that Trol is requiredContinue Reading