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Rosmarinic Acid--Pharmaceutical and Clinical Aspects.
This review compiles data from the Pubmed, Scopus, Scifinder, Web Of Science, and Science Direct databases published between 1990 and 2015, restricting the search to works with the keywords "Rosmarinic acid" in the title. Expand
The antidepressant-like effect of Hedyosmum brasiliense and its sesquiterpene lactone, podoandin in mice: evidence for the involvement of adrenergic, dopaminergic and serotonergic systems.
The results indicate that the antidepressant-like effect of H. brasiliense (and podoandin) is dependent on the serotonergic, noradrenergic and dopaminergic systems, but not on the GABAergic, opioid and oxidonitrergic systems. Expand
Herbalists, traditional healers and pharmacists: a view of the tuberculosis in Ghana
There is a clear distancing between the traditional healers and the conventional system, in Ghana, in terms of culture and modes of operation, each constituting isolated systems with little or no collaboration between them. Expand
Evaluation of behavioral and pharmacological effects of Hedyosmum brasiliense and isolated sesquiterpene lactones in rodents.
The results suggest that EEHb presents psychopharmacological activities, including anxiolytic, antidepressant, and hypnotic effects. Expand
Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer.
Results show that ARD, HDS and PDA significantly ameliorated the Aβ1-42 peptide-induced memory impairment in the passive avoidance task and may be potential candidates for Alzheimer's disease therapy. Expand
Sesquiterpene lactones from the leaves of Hedyosmum brasiliense (Chloranthaceae).
The isolation and identification of sesquiterpene lactones from the leaves of Hedyosmum brasiliense Miq. Expand
Effects of the topical application of an ethyl acetate fraction from Vernonia scorpioides on excisional wounds infected with Staphylococcus aureus in rats
Results support the effectiveness of V. scorpioides antimicrobial activity in infected wound healing in rats, demonstrated by the increased wound contraction, smaller area of necrotic tissue, good development of granulation tissue, extensive extracellular matrix deposition and epithelial regeneration. Expand
Sesquiterpene lactones from Hedyosmum brasiliense induce in vitro relaxation of rat aorta and corpus cavernosum
Hedyosmum brasiliense Miq., Chloranthaceae, has been used in Southern Brazil as a sedative, anti-inflammatory, and aphrodisiac. In this study, endothelium-intact and endothelium-denuded rat aorticExpand
Phytochemical analysis of the hot tea infusion of Hedyosmum brasiliense
The leaves of the neotropical dioecious shrub Hedyosmum brasiliense (HB) are employed popularly as a sedative, aphrodisiac and as a substitute for green tea. The aim of this work was to study theExpand