Hydrogenation of Hindered Ketones Catalyzed by a Silica-Supported Compact Phosphine—Rh System.
- Soichiro Kawamorita, G. Hamasaka, H. Ohmiya, K. Hara, A. Fukuoka, M. Sawamura
- Chemistry
- 10 March 2009
Directed ortho borylation of functionalized arenes catalyzed by a silica-supported compact phosphine-iridium system.
- Soichiro Kawamorita, H. Ohmiya, K. Hara, A. Fukuoka, M. Sawamura
- ChemistryJournal of the American Chemical Society
- 24 March 2009
An immobilized monophosphine-Ir system, which was prepared in situ from [Ir(OMe)(cod)](2) and a silica-supported, compact phosphine, showed high activities and selectivities for the borylation of…
Rh-catalyzed borylation of N-adjacent C(sp3)-H bonds with a silica-supported triarylphosphine ligand.
- Soichiro Kawamorita, T. Miyazaki, Tomohiro Iwai, H. Ohmiya, M. Sawamura
- ChemistryJournal of the American Chemical Society
- 26 July 2012
Direct C(sp(3))-H borylation of amides, ureas, and 2-aminopyridine derivatives at the position α to the N atom, which gives the corresponding α-aminoalkylboronates, has been achieved with a…
Rh-catalyzed ortho-selective C-H borylation of N-functionalized arenes with silica-supported bridgehead monophosphine ligands.
- Soichiro Kawamorita, T. Miyazaki, H. Ohmiya, Tomohiro Iwai, M. Sawamura
- Chemistry, BiologyJournal of the American Chemical Society
- 11 November 2011
The reaction showed significant tolerance toward steric repulsion around the reacting C-H bond, and the regioselectivity was excellent with various N-directing groups, including saturated and unsaturated N-heterocycles, tert-aminoalkyl groups, and imine-type C-N double bonds.
Iridium-catalyzed C–H borylation of quinolines and unsymmetrical 1,2-disubstituted benzenes: insights into steric and electronic effects on selectivity
- Hazmi Tajuddin, P. Harrisson, P. Steel
- Chemistry
- 29 October 2012
Borylation of quinolines provides an attractive method for the late-stage functionalization of this important heterocycle. The regiochemistry of this reaction is dominated by steric factors but, by…
Directed ortho borylation of phenol derivatives catalyzed by a silica-supported iridium complex.
- K. Yamazaki, Soichiro Kawamorita, H. Ohmiya, M. Sawamura
- ChemistryOrganic Letters
- 23 August 2010
The directed ortho borylation of phenol derivatives protected with an N,N-diethylcarbamoyl group was efficiently catalyzed by an immobilized monophosphine-Ir system, which was prepared in situ from…
Synthesis of primary and secondary alkylboronates through site-selective C(sp3)-H activation with silica-supported monophosphine-Ir catalysts.
- Soichiro Kawamorita, R. Murakami, Tomohiro Iwai, M. Sawamura
- ChemistryJournal of the American Chemical Society
- 15 February 2013
The site-selective activation and borylation of unactivated C(sp(3))-H bonds in 2-alkylpyridines to form primary and secondary alkylboronates was achieved using silica-supported monophosphine-Ir…
Site-selective C-H borylation of quinolines at the C8 position catalyzed by a silica-supported phosphane-iridium system.
- S. Konishi, Soichiro Kawamorita, Tomohiro Iwai, P. Steel, T. Marder, M. Sawamura
- ChemistryChemistry - An Asian Journal
- 1 February 2014
The efficient synthesis of a corticotropin-releasing factor1 (CRF1) receptor antagonist based on a late-stage C-H borylation strategy demonstrates the utility of the C8 borylated reaction.
Ester-directed regioselective borylation of heteroarenes catalyzed by a silica-supported iridium complex.
- Soichiro Kawamorita, H. Ohmiya, M. Sawamura
- Chemistry, BiologyJournal of Organic Chemistry
- 29 April 2010
The ester-directed regioselective borylation of arenes catalyzed by a silica-supported monophosphine-Ir complex displayed a significantly broad substrate scope toward heteroaromatic compounds,…
Palladium-catalyzed borylation of sterically demanding aryl halides with a silica-supported compact phosphane ligand.
- Soichiro Kawamorita, H. Ohmiya, Tomohiro Iwai, M. Sawamura
- ChemistryAngewandte Chemie
- 29 August 2011
Silica-SMAP, which is a silica-supported “compact” phosphane ligand, is developed and demonstrated that the surface-bound 1:1 metal/P complexes afford highly active catalysts for the hydrosilylation and the hydrogenation of ketones, and the directed ortho borylation of functionalized arenes.
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