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OBJECTIVE To compare the neuropathy associated with impaired glucose tolerance (IGT) and diabetes mellitus (DM) determined by oral glucose tolerance testing (OGTT). METHODS Patients with peripheral neuropathy of unknown cause were prescribed OGTT. Duration of neuropathic symptoms, neuropathic pain, neuropathy classification, nerve conduction test results,(More)
We sought to develop and validate a standardized cutaneous nerve regeneration model and to define the rate of epidermal nerve fibre (ENF) regeneration first in healthy control subjects and then in neuropathic and neuropathy-free subjects with diabetes. Next, we assessed the effect of different factors on the rate of nerve fibre regeneration and investigated(More)
Active Networks carry SmartPackets which contain both data and user-specified methods to extend the functionality of switches to perform user-specific computation on the encapsulated data. This enables rapid customization of the network and provides a mechanism to adapt the network to a changing environment. In this paper, we describe the implementation of(More)
OBJECTIVE Vigabatrin treatment is frequently associated with irreversible retinal injury and produces retinal electrophysiological changes in nearly all patients. Concern has been raised that tiagabine and other antiepilepsy drugs (AEDs) that increase brain gamma-aminobutyric acid (GABA) might produce similar electrophysiological and clinical changes in(More)
  • Shawn R Wolfe, Peter A Jarvis, Francis Y Enomoto, Maarten Sierhuis, Bart-Jan Van, Putten Kapil +1 other
  • 2008
Today's air traffic management system is not expected to scale to the projected increase in traffic over the next two decades. Enhancing collaboration between the controllers and the users of the airspace could lessen the impact of the resulting air traffic flow problems. We summarize a new concept that has been proposed for collaborative air traffic flow(More)
BACKGROUND In spite of some inherent limitations, naturalistic data can provide information on populations that have greater heterogeneity than can controlled clinical trials and on functional outcomes that may be especially important in clinical practice. In the present retrospective naturalistic study, we evaluated key clinical outcomes among the first(More)
  • Pat Pridmore, Chris Yates, Kate Kuhn, Helina Xerinda, E Barnett, K De Koning +69 others
  • 2006
Department For International Development. Each paper represents a study or piece of commissioned research on some aspect of education and training in developing countries. Most of the studies were undertaken in order to provide informed judgements from which policy decisions could be drawn, but in each case it has become apparent that the material produced(More)
Introduction Thus far, most of the research on both neurodevelopmental and neurodegenerative disorders has been focused on finding the presumed underlying genetic causes, while much less emphasis has been put on potential environmental factors. While some forms of autism are clearly genetic, the fact remains that heritability factors cannot adequately(More)
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