Sofya Suidasari

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Dietary supplemental vitamin B6 increases carnosine and anserine concentrations in the heart of rats

Sofya Suidasari, Tomoko Hasegawa, Noriyuki Yanaka, Norihisa Kato
SpringerPlus
2015

This study was performed to examine the effect of dietary level of vitamin B6 on the concentrations of carnosine and anserine, antioxidants, in the heart of rats. Analysis using UPLC-MS/MS showed… (More)

Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation.

Peipei Zhang, Kohsuke Tsuchiya, +6 authors Takashi Suda
The Journal of biological chemistry
2016

Vitamin B6 includes six water-soluble vitamers: pyridoxal (PL), pyridoxamine (PM), pyridoxine (PN), and their phosphorylated forms. Pyridoxal 5'-phosphate (PLP) is an important cofactor for many… (More)

Consumption of vitamin B(6) reduces fecal ratio of lithocholic acid to deoxycholic acid, a risk factor for colon cancer, in rats fed a high-fat diet.

Yukako Okazaki, Zaki Utama, +5 authors Norihisa Kato
Journal of nutritional science and vitaminology
2012

To examine the effect of supplemental dietary vitamin B(6) on the colonic luminal environment, growing male rats were fed a high-fat diet containing 1, 7, or 35 mg pyridoxine HCl/kg diet for 6 wk.… (More)

Carnosine Content in Skeletal Muscle Is Dependent on Vitamin B6 Status in Rats

Sofya Suidasari, Jan Stautemas, Shinji Uragami, Noriyuki Yanaka, Wim Derave, Norihisa Kato
Front. Nutr.
2015

Carnosine, a histidine-containing dipeptide, is well known to be associated with skeletal muscle performance. However, there is limited information on the effect of dietary micronutrients on muscle… (More)

Dietary vitamin B6 modulates the gene expression of myokines, Nrf2-related factors, myogenin and HSP60 in the skeletal muscle of rats.

Sofya Suidasari, Shinji Uragami, Noriyuki Yanaka, Norihisa Kato
Experimental and therapeutic medicine
2017

Previous studies have suggested that vitamin B6 is an ergogenic factor. However, the role of dietary vitamin B6 in skeletal muscle has not been widely researched. The aim of the present study was to… (More)

Comparative study on the responses of concentrations of B₆-vitamers in several tissues of mice to the dietary level of pyridoxine.

Kabo Masisi, Sofya Suidasari, Peipei Zhang, Yukako Okazaki, Noriyuki Yanaka, Norihisa Kato
Journal of nutritional science and vitaminology
2012

To examine the responses of the levels of B₆-vitamers in several tissues to the dietary level of pyridoxine (PN), mice were fed diets containing 0, 1, 7 (the recommended level) or 35 mg PN HCl/kg… (More)

Vitamin B₆ activates p53 and elevates p21 gene expression in cancer cells and the mouse colon.

Peipei Zhang, Sofya Suidasari, Tomomi Hasegawa, Noriyuki Yanaka, Norihisa Kato
Oncology reports
2014

Increasing evidence indicates vitamin B6 acts as a protective factor against colon cancer. However, the mechanisms of the effect of vitamin B6 are poorly understood. The present preliminary study… (More)

High concentrations of pyridoxal stimulate the expression of IGFBP1 in HepG2 cells through upregulation of the ERK/c‑Jun pathway.

Peipei Zhang, Sofya Suidasari, Tomomi Hasegawa, Noriyuki Yanaka, Norihisa Kato
Molecular medicine reports
2013

Increasing evidence suggests that dietary vitamin B6 is linked to the prevention of cancer and cardiovascular disease. However, the molecular mechanisms involved in this process are not yet… (More)

Effects of low dose of ethanol on the senescence score, brain function and gene expression in senescence-accelerated mice 8 (SAMP8)

Akiko Kimoto, Hanae Izu, Churan Fu, Sofya Suidasari, Norihisa Kato
Experimental and therapeutic medicine
2017

Accumulating epidemiological evidence suggests light to moderate alcohol intake reduces risk of several chronic diseases. However, there is limited information regarding the effects of low alcohol… (More)

Study on the influence of dietary vitamin B 6 on heart and skeletal muscles

Sofya Suidasari
2015

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