Sofiyan Saleem

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Transient global cerebral ischemia causes delayed neuronal death in the hippocampal CA1 region. It also induces an up regulation of cyclooxygenase 2 (COX-2), which generates several metabolites of arachidonic acid, known as prostanoids, including Prostaglandin I2 (PGI2). The present study investigated whether the PGI2 IP receptor plays an important role in(More)
The Author Contributions section now reads: S.A.L. designed and supervised all experiments and prepared the manuscript. Y.W. and J.W.L. performed chemical synthesis of aminoadamantane nitrates, analysis of the structure-activity relationship, and hit-to-lead optimi-This work is licensed under a Creative Commons Attribution 4.0 International License. The(More)
Beraprost sodium is a new stable, orally active Prostaglandin I2 analogue. The aim of this study was to determine the effect of beraprost on cognitive dysfunction and locomotor impairment induced by bilateral common carotid artery occlusion in mice. We investigated the ameliorating effect of beraprost through PGI2 IP receptor by studying neurologic deficit(More)
Information flow security is branch of computer science aimed at regulating of the dissemination of information in programs, that is, to preventing the inadvertent flow of private information handled by computer programs to unauthorized public entities. Although static systems for programming language based information flow control are well-studied, few(More)
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