Sofiene Bouaziz

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We have applied NMR and molecular dynamics computations including intensity based refinement to define the structure of the d(G-G-G-C-T4-G-G-G-C) dodecanucleotide in 100 mM NaCl solution. The G-G-G-C sequence is of interest since it has been found as tandem repeats in the DNA sequence of human chromosome 19. The same G-G-G-C sequence is also seen as islands(More)
We have identified a unique structural transition (in slow exchange on the NMR time scale) in the tertiary fold of the d(G-G-G-C-T4-G-G-G-C) quadruplex on proceeding from Na+ to K+ as counterion in aqueous solution. Both monovalent cation-dependent conformations exhibit certain common structural features, which include head-to-tail dimerization of two(More)
The wireless measurement of various physical quantities from the analysis of the RADAR Cross Sections variability of passive electromagnetic sensors is presented. A millimetre-wave Frequency-Modulated Continuous-Wave RADAR is used for both remote sensing and wireless identification of sensors. Long reading ranges (up to some decameters) may be reached at(More)
This paper presents the design and experimental validation of an original single layer planar wideband microstrip antenna for C-band airborne applications. This antenna printed on a 787μm-thick substrate exhibits wideband performance and inclined radiation patterns. The measured results are in good agreement with the simulated ones in terms of bandwidth(More)
A combined NMR-molecular dynamics approach has been applied to determine the solution structure of a truncated analogue of the Bombyx mori telomeric d(TTAGG) single repeat sequence in Na+ cation-containing aqueous solution. The two-fold symmetric four-stranded d(TAGG) quadruplex contains two adjacent G(syn).G(syn).G(anti).G(anti) G-tetrads sandwiched(More)
A novel wireless and passive temperature sensor that utilizes microfluidic and liquid metal technologies for the temperature-dependent modification of the sensor’s radar echo is introduced. Liquid metal is used to dynamically alter the number of antenna elements activated along a linear array configuration with respect to temperature. In this way, the(More)
A novel 1H-13C correlated two-dimensional experiment, CT-HMQC-J, for the measurement of three-bond proton-phosphorus coupling constants in 13C-labeled DNA is described. The experiment is based on the intensity difference of 1H-13C cross peaks in the presence and absence of the proton-phosphorus coupling interaction during the constant-time period in HMQC(More)
We present a new miniaturized (below 1 mm ) temperature sensor based on microfluidic technology and radar passive interrogation principles, which can be easily applied for temperature telemetry for medical applications. The chipless microsystem is made up of a planar-gap capacitor with a microchannel located in between its plates. The temperature-dependent(More)
BACKGROUND Triplet repeat sequences are of considerable biological importance as the expansion of such tandem arrays can lead to the onset of a range of human diseases. Such sequences can self-pair via mismatch alignments to form higher order structures that have the potential to cause replication blocks, followed by strand slippage and sequence expansion.(More)
In this paper, we present the wirelessmeasurement of various physical quantities from the analysis of the radar cross section variability of passive electromagnetic sensors. The technique uses a millimeter frequency-modulated continuous-wave radar for both remote sensing and wireless identification of sensors. Long reading ranges (up to some decameters) are(More)