Sofia S. Haque

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Intracranial aneurysms in infants and children

Janice W. Allison, Patricia C. Davis, +4 authors C M Glasier
Pediatric Radiology
1998

Background. The diagnosis and imaging of pediatric aneurysms has changed since the advent of MR and MRA. Objective. To update the literature on pediatric aneurysms and better define the appropriate… (More)

Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer.

Alan Ho, Ravinder Kaur Grewal, +14 authors James A. Fagin
The New England journal of medicine
2013

BACKGROUND Metastatic thyroid cancers that are refractory to radioiodine (iodine-131) are associated with a poor prognosis. In mouse models of thyroid cancer, selective mitogen-activated protein… (More)

Spectrum of central nervous system abnormalities in neurocutaneous melanocytosis.

Vijay Ramaswamy, Holly Delaney, Sofia S. Haque, Ashfaq A. Marghoob, Yasmin N Khakoo
Developmental medicine and child neurology
2012

AIM Neurocutaneous melanocytosis is a rare neurocutaneous syndrome defined by the presence of large and/or multiple congenital cutaneous nevi and melanocytic deposits in the central nervous system.… (More)

A randomized phase II study of cetuximab every 2 weeks at either 500 or 750 mg/m2 for patients with recurrent or metastatic head and neck squamous cell cancer.

Matthew G. Fury, Eric J Sherman, +16 authors David G. Pfister
Journal of the National Comprehensive Cancer…
2012

Cetuximab is typically administered on a weekly schedule for patients with recurrent or metastatic head and neck squamous cell cancer (HNSCC). This study explores cetuximab administered every 2 weeks… (More)

Evaluation of romidepsin for clinical activity and radioactive iodine reuptake in radioactive iodine-refractory thyroid carcinoma.

Eric J Sherman, Yungpo Bernard Su, +8 authors David G. Pfister
Thyroid : official journal of the American…
2013

BACKGROUND Historically, systemic therapy for radioactive iodine (RAI)-refractory thyroid cancer has been understudied. Available drugs have modest efficacy. Romidepsin is a histone deacetylase… (More)

Phase II trial of bevacizumab + cetuximab + cisplatin with concurrent intensity-modulated radiation therapy for patients with stage III/IVB head and neck squamous cell carcinoma.

Matthew G. Fury, Han Xiao, +14 authors David G. Pfister
Head & neck
2016

BACKGROUND The purpose of this study was to evaluate the efficacy and tolerability of the addition of 2 monoclonal antibodies, bevacizumab and cetuximab, to 2 cycles of high-dose cisplatin… (More)

A phase II open-label study of ganetespib, a novel heat shock protein 90 inhibitor for patients with metastatic breast cancer.

Komal L Jhaveri, Sarat Chandarlapaty, +18 authors Shanu Modi
Clinical breast cancer
2014

BACKGROUND Ganetespib is a small molecule, nongeldanamycin HSP90 inhibitor with potent inhibitory effects on HSP90-dependent oncoproteins of relevance to breast cancer pathogenesis. We therefore… (More)

A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer.

Matthew G. Fury, Eric J Sherman, +8 authors David G. Pfister
Cancer
2013

BACKGROUND Activation of the phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is common in head and neck cancers, and it has been demonstrated that inhibition of… (More)

Phase 2 study evaluating the combination of sorafenib and temsirolimus in the treatment of radioactive iodine-refractory thyroid cancer.

Eric J Sherman, Lara A Dunn, +8 authors David G. Pfister
Cancer
2017

BACKGROUND Patients with recurrent and/or metastatic, radioactive iodine-refractory thyroid carcinoma have limited treatment options. Sorafenib, an oral kinase inhibitor, is approved by the US Food… (More)

Extraneural ependymoma: distant bone, lung, liver, and lymph node metastases following bevacizumab.

Cheryl Fischer, Sofia S. Haque, +4 authors Yasmin N Khakoo
Pediatric blood & cancer
2013

Extraneural metastases of ependymoma are rare, and have been reported in the lungs, lymph nodes, pleura, mediastinum, liver, diaphragmatic muscle, and bone. We report a case of anaplastic ependymoma… (More)

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