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Microleakage has been discussed as a major contributing factor for inflammatory reactions at the implant-abutment connection. In previous studies, the tightness against corpuscular bodies (viable bacteria) has been successfully investigated under static and dynamic conditions. The aim of this study was to investigate the tightness against endotoxins of two(More)
OBJECTIVE The aim of this in vitro study was to assess lipopolysaccharide microleakage at conical implant-abutment connections of two-piece dental implants in terms of the expression levels of genes involved in lipopolysaccharide-mediated proinflammatory cytokine production. MATERIALS AND METHODS Two implant systems with conical implant-abutment(More)
Repeated exposure to high concentrations of ozone results first in augmentation (typically on the second day) and then attenuation of pulmonary response in humans. To determine the effects of repeated prolonged low-concentration ozone exposure, we exposed 17 healthy nonsmoking male subjects to 0.12 ppm ozone for 6.6 h on 5 consecutive days. Subjects were(More)
The purpose of this prospective study was to evaluate the clinical outcome of three- to four-unit posterior all-ceramic fixed dental prostheses (FDPs) made of yttria-stabilized tetragonal zirconia-polycrystal ceramic frameworks (CerconBase; Degudent). Fifty-eight restorations were placed in 48 patients. Twenty-four FDPs had an end abutment design (EAD)(More)
Metastases arise from disseminated tumor cells (DTC) that colonize secondary organs. However, DTC survival strategies to start metastatic outgrowth are unclear. The hostile (hypoxic, hypoglycemic) microenvironmental conditions of the bone marrow serve as an ideal model environment for investigation of DTC survival strategies under environmental stress. We(More)
Dissemination of primary cancer cells to distant sites is an early event in breast cancer. These cells can invade the bone marrow, rest there, and many years later disseminated tumor cells (DTC) can grow out to form overt metastases. Epithelium specific cytokeratins are commonly used as marker proteins for sensitive detection of metastatic lesions. However,(More)
PURPOSE Intraosseous heat development is always a problem during bone surgery performed using rotary burs and ultrasound devices. However, only few data exist regarding the morphological effects of applied heat on bone surfaces. METHODS We used 24 human mandibular bone specimens of the mental region from six body donators. Three body donators were fixed(More)
OBJECTIVES The aim of this preliminary prospective study was to evaluate the clinical outcome, the oral health-related quality of life (OHRQoL), and the subjective chewing ability of patients with mandibular complete dentures retained by a single implant placed in the mandible midline. METHODS Patients wearing complete dentures were treated with a single(More)
UNLABELLED We analysed the effects of all-trans retinoic acid (ATRA) on proliferation and changes in the global proteome of the nullipotent human embryonal carcinoma cell line 2102Ep and the pluripotent cell line NTERA2 cl.D1 (NT2). Differentially expressed proteins were assessed by 2D-PAGE and mass spectrometry, followed by verification and analysis of(More)
Our aim was to evaluate the intrabony friction heat produced by implant drills, using different drill materials and methods of cooling. Four pilot drills and 4 form drills were used. The following combinations of drill material and cooling supply were tested: steel and external cooling; steel and internal cooling; steel coated with zirconium nitride and(More)