Socorro Rodríguez Holguín

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The goal of this study was to assess the P3a component of event-related potentials in a population of abstinent, chronic alcoholics. A three-stimulus visual oddball paradigm was used to elicit robust P3a components in a large group of well-characterized male alcoholics (n = 44) and controls (n = 28). The task required subjects to make a difficult perceptual(More)
BACKGROUND Voltage of the P300 component of event-related potentials (ERPs) has been proposed as a phenotypic marker of risk for alcoholism. P3a elicited by intrusive events is important in the context of deficits in inhibition found during psychophysiological and behavioral evaluations in children of alcoholics. METHODS ERPs were recorded from a group of(More)
The aim of the present study was to determine how binge drinking (BD) affects brain functioning in male and female university students during the performance of a visual discrimination task. Thirty two binge drinkers and 53 controls (non binge drinkers), with no history of other drug use, personal or family history of alcoholism or psychopathological(More)
AIMS The objective of this study was to examine brain activity, with particular attention to prefrontal function, during response execution and inhibition in youths who have engaged in binge drinking (BD) for at least 2 years. DESIGN Event-related potentials (ERPs) were recorded twice within 3 years, during performance of a Go/NoGo task. SETTING The(More)
Event-related potentials (ERPs), particularly the P3 wave, have been proposed as biological markers of genetic risk for alcoholism. The present study assesses the ERPs from 102 boys and girls (7 to 15 years old) divided into three groups: two groups of sons and daughters of alcoholic fathers, with and without other first- or second-degree relatives(More)
The mismatch negativity (MMN) component of event-related potentials was recorded from a group of young children of alcoholics (n = 19, 8 females) with a high-density family history of alcoholism and from a control group (n = 23, 12 females), between 8 and 15 years of age. A dichotic listening task was used, and subjects had to pay attention to an oddball(More)
Event-related potentials (ERPs) were recorded from a group of young children of alcoholics (HR; n = 17, 7 females) with a high-density family-history of alcoholism and from a control group (CN; n = 19, 10 females), ages 7-15 years old, during a visual continuous performance task. The P3 peak amplitude and the mean amplitude at five latency windows (300-800(More)
OBJECTIVE The varying results of visual event-related potential (ERP) studies of central and peripheral cueing suggest that these types of cue may modulate stimuli processing with different time courses. The aim of this study was to investigate differences in the time course of facilitatory effects on the visual processing induced by peripheral and central(More)
BACKGROUND Binge drinking (BD) is prevalent among college students. Studies on alcoholism have shown that the prefrontal cortex is vulnerable to the neurotoxic effects of alcohol. The prefrontal cortex undergoes both structural and functional changes during adolescence and young adulthood. Sex differences have been observed in brain maturation and in(More)
BACKGROUND Adolescence is a time of considerable neurodevelopment. Binge drinking (BD) during this period increases the vulnerability to its neurotoxic effects. This longitudinal study aimed to investigate the relationship between BD trajectory over university years and neuropsychological functioning. METHODS Cohort-study. Two-year follow-up. A total of(More)