Slobodan I Obradović

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BACKGROUND Rett syndrome (RTT) is a severe neurodevelopmental disorder that represents the second most common cause of mental retardation in females. However, incidence and prevalence of RTT are scarcely reported. METHODS A retrospective study included all patients with RTT diagnosed between 1981 and 2012 in Serbia. Estimation of incidence and prevalence(More)
The purpose of this study is to investigate the effect of two of the most important functional CYP1A2 variations −3860G > A and −163C > A on carbamazepine pharmacokinetics in Serbian pediatric epileptic patients. The study involved 40 Serbian pediatric epileptic patients on steady-state carbamazepine treatment. Genotyping for −3860G > A and −163C > A was(More)
The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment. Genotyping was conducted using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), and allele-specific(More)
BACKGROUND The diagnosis of growth hormone (GH) deficiency in adults is based on provocative testing of GH secretion. The insulin tolerance test (ITT), currently the favoured test for this diagnosis, has been criticised for poor reproducibility and inconvenience. Since the combined administration of GH-releasing hormone (GHRH) plus GH-releasing peptide-6(More)
As an organ responsible for generation of T-cell repertoire the thymus occupies a central position in establishment of mature immune response. To assess the potential role of the gonadal steroids in development and maintenance of immunological sexual dimorphism, the effects of gonadectomy pre- and postpuberty on the thymocyte profile of male and female rats(More)
Stress hyperglycemia represents increased blood glucose level that is result of activation of neurohormonal processes in organism exposed to stress. The aim of the paper is to analyze literature data on prognostic implications of admission hyperglycaemia in patients with acute myocardial infarction (AMI). Retrospective study included 543 patients with AMI(More)
—Changes in the network topology such as large-scale power outages or Internet worm attacks are events that may induce routing information updates. Border Gateway Protocol (BGP) is by Autonomous Systems (ASes) to address these changes. Network reachability information, contained in BGP update messages, is stored in the Routing Information Base (RIB). Recent(More)
Cognitive impairment is present in up to 65 % of multiple sclerosis (MS) patients. The Brief Repeatable Battery of neuropsychological tests (BRB) is one of the most used neuropsychological tools for cognitive assessment in MS. However, relative lack of normative data limits its application in research and clinical practice. In order to obtain normative data(More)
  • Vojnosanitetski Pregled, Russia Andrej Aleksandrov, Assoc Prof Kiyoshi, Ameno, Japan Rocco Bellantone, Hod Hanoch +71 others
  • 2012
Kopiju uplatnice dostaviti na gornju adresu. Određivanje morfina, kodeina i 6-monoacetilmorfina metodom HPLC/MS u salivi heroinskih zavisnika Determination of morphine, codeine and 6-monoacetylmorphine in saliva of substance-abuse patients using HPLC/MS methods.. Glycosaminoglycans in the urinary bladder mucosa, tumor tissue and mucosal tissue around tumor(More)