Slavomír Horňák

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OBJECTIVE To assess the sedative and immobilization effect of intranasal administration (INS) of midazolam (MID) without or with INS dexmedetomidine (DXM), and some physiological changes induced by the drugs. The ability of INS atipamezole to reverse the DXM component was also assessed. STUDY DESIGN Prospective 'blinded' experimental study. ANIMALS In(More)
Rabbit chondrocytes were cultivated in vitro using the collagen/hyaluronan membrane. The membrane did not show any adverse effects on chondrocyte viability during in vitro cultivation. The inoculated cells grew without any negative changes. According to the histochemical analyses: (i) hematoxylin and eosin; (ii) safranin O; and (iii) rabbit anti-human(More)
Cartilage tissue engineering can provide substantial relief to people suffering from degenerative cartilage disease, such as osteoarthritis. The autologous platelet-rich plasma (PRP) application appears to improve cartilage healing due to its ability to positively influence cellular mechanisms, mainly in cells from synovium and cartilage. Primary cultures(More)
OBJECTIVE The aim of our study was to evaluate, from a histological point of view, the effect of photobiomodulation (PBM) with combined low-level laser therapy (LLLT)/light- emitting diode (LED) on porcine skin wound healing. BACKGROUND DATA Most LLLT/LED wound healing studies have been performed on various types of rat models, with their inherent(More)
The aim of this study was to monitor short-term osteoarthrosis progress in relation to a recently introduced novel extracapsular method called the Tight Rope procedure and after Lateral Suture with nylon in cruciate-deficient dog stifle joints. Twelve dogs were included in the study. Treatment type was not randomised. Mediolateral radiographs from 12 stifle(More)
Objective This study aimed to compare microfracture and application of adipose-derived stem cells (ADSCs) by local adherent technique enhanced by platelet-rich plasma (PRP) to provide a new approach for the repair of cartilage defect. Design Full-thickness cylindrical defects were created in the medial femoral condyle in 9 New Zealand White rabbits (5(More)
Avian osteoblasts have been isolated particularly from chicken embryo, but data about other functional tissue sources of adult avian osteoblast precursors are missing. The method of preparation of pigeon osteoblasts is described in this study. We demonstrate that pigeon cancellous bone derived osteoblasts have particular proliferative capacity in vitro in(More)
Sheep were used as a model for the examination of radiological and histological changes in bone tissue following total hip replacement. A unilateral total hip replacement procedure was carried out in sheep with radiological examinations at 1, 3 and 6 months after surgery. After six moths, the sheep were euthanized and the bone tissue was collected for(More)
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