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As an alternative to the watermarking approach, content-based copy detection (CBCD) recently has become a promising technique for video monitoring and copyright protection. In this paper, a novel CBCD framework is proposed. Firstly, robust global feature (DCT), local features (SIFT) and audio feature (EDF) are first combined to describe video and audio(More)
It is suspected that some neurodegenerative diseases are a result of the disturbance of copper (Cu) homeostasis, although it remains unclear whether the disturbance of Cu homeostasis has aberrant effects on neurons. Herein, we investigated Cu metabolism specifically in neurons in terms of changes in the intracellular Cu concentration and the expression of(More)
In this paper, we present a new variations of the popular nonnegative matrix factorization (NMF) approach to extend it to the data with negative values. When a NMF problem is formulated as X ≈ HW, we try to develop a new method that only allows W to contain nonnegative values, but allows both X and H to have both nonnegative and negative values. In(More)
AIMS Sigma-1 receptor (Sig-1R) is a ligand-regulated endoplasmic reticulum (ER) chaperone involved in cardiac hypertrophy, but it is not known whether Sig-1R is regulated by microRNAs (miRNAs). According to bioinformatic analysis, miR-297 was suggested as a potential target miRNA for Sig-1R. Therefore, we verified whether miR-297 could target Sig-1R and(More)
In this paper, we describe BUPT-MCPRL systems for TRECVID 2011. Our team participated in five tasks: semantic indexing, known-item search, instance search content-based copy detection and surveillance event detection. A brief introduction is shown as follows: In this year, we proposed two different methods: one based on text and another is bio-inspired(More)
NADPH oxidase 4 (NOX4) and the NOX4-related redox signaling are implicated in cardiac hypertrophy. NOX4 is interrelated with endoplasmic reticulum stress (ERS). Spliced X-box binding protein 1 (Xbp1s) is a key mediator of ERS while its role in cardiac hypertrophy is still poorly understood. Recently, receptor interacting protein kinase 1(RIPK1) has been(More)
The present study aimed to investigate miR-590-3p's role in osteogenic differentiation of human mesenchymal stem cells (hMSC). HMSC were cultured and transfected with empty vector, miR-590-3p vector to construct control hMSC and miR-590-3p overexpression hMSC. MiR-590-3p suppressed hMSC was created with oligonucleotide transient transfection. All 3 groups(More)
Palmitic acid (PA) is known to cause cardiomyocyte dysfunction. Cardiac hypertrophy is one of the important pathological features of PA-induced lipotoxicity, but the mechanism by which PA induces cardiomyocyte hypertrophy is still unclear. Therefore, our study was to test whether necroptosis, a receptor interacting protein kinase 1 and 3 (RIPK1 and RIPK3-)(More)
The aim of this study is to construct specific shRNA expressing plasmids, and to observe their effects on H9c2 cardiomyocytes injury induced by hypoxia/reoxygenation (H/R). RIPK1 and RIPK3 are the key kinases mediating the process of necroptosis. Using recombinant DNA technology, we inserted the synthetic shRNA into pSUPER vector to construct RIPK1-shRNA or(More)