Siyu Wang

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For eukaryotic cells, the biological processes involving regulatory DNA elements play an important role in cell cycle. Understanding 3D spatial arrangements of chromosomes and revealing long-range chromatin interactions are critical to decipher these biological processes. In recent years, chromosome conformation capture (3C) related techniques have been(More)
Colon cancer classification has a significant guidance value in clinical diagnoses and medical prognoses. The classification of colon cancers with high accuracy is the premise of efficient treatment. Our task is to build a system for colon cancer detection and classification based on slide histopathological images. Some former researches focus on single(More)
The oncogenic STAT3 signaling pathway is emerging as a promising target for the treatment of multiple myeloma (MM). In the present study, we identified a novel STAT3 inhibitor SC99 in a target-based high throughput screen. SC99 inhibited JAK2-STAT3 activation but had no effects on other transcription factors such as NF-κB, and kinases such as AKT, ERK, and(More)
Skin-derived precursors (SKPs) from dermis possess the capacities of self-renewal and multipotency. In vitro and in vivo studies demonstrated that they can differentiate into fibroblasts. However, little is known about the molecular mechanism of the differentiation of SKPs into fibroblasts. Here we compare the transcriptomes of mouse SKPs and SKP-derived(More)
Research progress in membrane water treatment technology during 1985–2013 was analyzed based on the bibliometric analysis of published papers in ISI Web of Science Core Collection (Science Citation Index-Expanded, SCI-E) database, and patents in Derwent Innovation Index database. The searched data (18,075 SCI papers and 19,182 patents) were statistically(More)
Four microalgae species were isolated from freshwaters in Xinjiang, one of which was identified as Scenedesmus sp.-BH. Analysis of the specimens showed not only the characterization of self-flocculation with a flocculating rate of 92.29 % in 12 h, but relatively high biomass and intracellular polysaccharide (IPS) production (250.5 and 5.55 mg/L) under(More)
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