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- Publications
- Influence
CHK1-CENP B/MAD2 is associated with mild oxidative damage-induced sex chromosome aneuploidy of male mouse embryos during in vitro fertilization.
- Yue Huang, Siyao Ha, Z. Li, Jiena Li, W. Xiao
- Biology, Medicine
- Free radical biology & medicine
- 1 June 2019
A high incidence of aneuploidy is observed in vitro fertilization (IVF)-derived embryos, but the formation and repair mechanisms are unknown. Here, we investigated the effects of slightly increased… Expand
Aurora B prevents aneuploidy via MAD2 during the first mitotic cleavage in oxidatively damaged embryos
- J. Li, Siyao Ha, Zhiling Li, Y. Huang, En Lin, W. Xiao
- Biology, Medicine
- Cell proliferation
- 1 July 2019
A high rate of chromosome aneuploidy is exhibited in in vitro fertilization (IVF)‐derived embryos. Our previous experiments suggested that reactive oxygen species (ROS) can activate Mad2, a key… Expand
Excess Palmitate Induces Decidual Stromal Cell Apoptosis Via the TLR4/JNK/NF-kB Pathways and Possibly through Glutamine Oxidation.
- Siyao Ha, Xue-min Qiu, +7 authors Mingqing Li
- Biology, Medicine
- Molecular human reproduction
- 16 January 2020
During gestation, excess palmitate (PA) is enriched in decidua. Both excess PA and decidual dysfunctions are associated with numerous adverse pregnancy outcomes such as gestational diabetes,… Expand
IL-2 and IL-27 synergistically promote growth and invasion of endometriotic stromal cells by maintaining the balance of IFN-γ and IL-10 in endometriosis.
- Xue-min Qiu, Zhen-Zhen Lai, +11 authors M. Li
- Chemistry, Medicine
- Reproduction
- 1 December 2019
Immune cells and cytokines have important roles in the pathogenesis of endometriosis. However, the production and role of cytokines of T helper type 1 (Th1) and Th2 cells in the progress of… Expand
The application of aspirin in pregnancy-related complications
- Lu-Yu Ruan, Zhen-Zhen Lai, +5 authors Mingqing Li
- Medicine
- 1 July 2020
Aspirin, one of the most widely applied medicines, not only possesses the effects on reducing fever, anti-vascular hyperplasia, and anti-inflammation, but also has the capacity of preventing platelet… Expand
Cyclooxygenase-2 and decidual immune cells
- Siyao Ha, Hui-Li Yang, Zhen-Zhen Lai, Lu-Yu Ruan, Jia-wei Shi, Mingqing Li
- Chemistry
- 1 July 2019
Cyclooxygenase-2 (COX-2) is a rate-limiting enzyme in arachidonic acid (AA) metabolism. COX-2 and its products (prostanoids) serve versatile biological functions during pregnancy. Numerous evidences… Expand