Sithembile Ruzario

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Background The Medical Research Council of Zimbabwe (MRCZ) houses the National Ethics Committee which safeguards the rights, safety and well-being of all research participants. Research participants in AIDS Prevention Trials, including HIV/AIDS vaccine trials, do from time to time have complaints during research implementation. The National Ethics Committee(More)
Background The Medical Research Council of Zimbabwe (MRCZ) is the National Ethics Committee in Zimbabwe. MRCZ was established in 1974 under the Research Act of 1959 and Government Notice No. 225 of 1974 to promote and coordinate health research in Zimbabwe. The main mandate of MRCZ is the scientific review, ethics approval and oversight of all ongoing(More)
Background Ensuring informed consent is a complicated component of clinical trials particularly with HIV prevention trials conducted in resource-limited settings. An inherent challenge of the informed consent process for HIV prevention studies is making sure trial participants understand that their participation does not increase exposure to HIV.(More)
Some of the secondary findings from the circumcision studies conducted in Africa, are both interesting and difficult to explain. This paper focuses on the finding that uncircumcised men who waited for ten minutes after sexual intercourse and then wiped their penises using a dry cloth, had lower rates of HIV infection compared to those who cleaned using a(More)
Background As efforts in search of effective HIV prevention strategies intensify, studies have become exceedingly complex, posing several regulatory challenges to most African Ethics Committees, the MRCZ included. Challenges faced include: Researchers not being clear on how to operate in compliance to local and sponsor country regulations; i.e. when a host(More)
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