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BACKGROUND Accelerated telomere shortening may cause cancer via chromosomal instability, making it a potentially useful biomarker. However, publications on blood telomere length (BTL) and cancer are inconsistent. We prospectively examined BTL measures over time and cancer incidence. METHODS We included 792 Normative Aging Study participants with 1-4 BTL(More)
Polymorphisms in pre‑microRNAs (miRNAs) or mature miRNAs may influence miRNA processing or target binding, thus contributing to tumorigenesis and cancer development. The present study aimed to evaluate whether miR‑149 rs2292832 (C>T) and miR‑608 rs4919510 (G>C) are associated with the risk and clinical characteristics of hepatocellular carcinoma (HCC) in a(More)
BACKGROUND Chronic inflammation plays a key role in cancer etiology. DNA methylation modification, one of the epigenetic mechanisms regulating gene expression, is considered a hallmark of cancer. Human and animal models have identified numerous links between DNA methylation and inflammatory biomarkers. Our objective was to prospectively and longitudinally(More)
In this work, we have developed an approach to include global illumination effects into Chinese Paintings (see Figure 1). Our method provides a robust approach to represent tone and value in a way similar to how Chinese Ink-and-Brush is painted. The method, especially, supports reflection, shadow, atmospheric, depth and weathering effects. Using the method,(More)
In this work, we present a simple mathematical approach to art directed shader development. We have tested this approach over two semesters in an introductory level graduate rendering & shading class at Texas A&M University. The students in the class each chose an artist's style to mimic, and then easily created rendered images strongly resembling(More)
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