Learn More
BACKGROUND Premature shortening of leukocyte telomere length has been proposed as a novel mechanism by which depression may confer increased risk of adverse cardiovascular events. Prior studies demonstrating associations of depression and depressive symptoms with shorter leukocyte telomere length were small, included selected psychiatric outpatients, were(More)
BACKGROUND Many acute coronary syndrome (ACS; myocardial infarction and unstable angina) patients are rehospitalized within 30 days of discharge, and recent US health policy initiatives have tied hospital Medicare reimbursement to 30-day readmission rates. Patient-perceived psychological stress is thought to impact prognosis after ACS. A recently offered(More)
like the patients they serve, often lack the knowledge and practical experience to pro-actively advise their patients. Many medical students and physicians feel ill-equipped to counsel overweight or obese patients. 7-9 As such, we need enhanced educational efforts aimed at translating decades of nutrition science into practical strategies whereby healthy,(More)
BACKGROUND Sudden death (SD) is a frequent catastrophic complication in patients after myocardial infarction. Circumstances of SD may affect strategies for prevention. METHODS AND RESULTS We reviewed source documentation for 1067 patients who had SD in the Valsartan in Acute Myocardial Infarction Trial (VALIANT) trial. We determined the circumstances of(More)
BACKGROUND Medication non-adherence continues to be a major challenge facing the healthcare system. A case is presented of a 48-year-old man with myocardial infarction who was found to be non-adherent to multiple medications. Conceptual models are reviewed along with current approaches for assessment and treatment of medication non-adherence. DESIGN Case(More)
OBJECTIVE When advising patients about possible initiation of primary prevention treatment, clinicians currently do not have information on expected impact on lifespan, nor how much this increment differs between individuals. METHODS First, UK cardiovascular and non-cardiovascular mortality data were used to calculate the mean lifespan gain from an(More)
We sought to determine whether cognitive function in stable outpatients with heart failure (HF) is affected by HF severity. A retrospective, cross-sectional analysis was performed using data from 2, 043 outpatients with systolic HF and without prior stroke enrolled in the Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial.(More)
OBJECTIVE Shared decision-making (SDM) is increasingly promoted in the primary care setting, but depressive symptoms, which are associated with cognitive changes, may influence decision-making preferences. We sought to assess whether elevated depressive symptoms are associated with decision-making preference in patients with comorbid chronic illness. (More)
T he association between heart failure and stroke risk has been described for >3 decades. 1 Hypercoagulability and left ventricular blood stasis are thought to contribute to stroke risk in patients with heart failure, 2 in addition to common risk factors such as hypertension and atrial fibrillation. Regardless of the mechanism, however, for the majority of(More)
  • 1