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Dear Editor, End-binding protein 1 (EB1), a member of microtubule plus-end tracking proteins (+TIPs), plays an important role in the regulation of microtubule dynamics and has been implicated in cancer development (Dong et al., 2010; Gouveia and Ak-hmanova, 2010; Wang et al., 2005). However, it remains poorly understood how EB1 functions are regulated by(More)
Pancreatic cancer has an extremely grim prognosis, with an overall 5-year survival rate less than 5%, as a result of its rapid metastasis and late diagnosis. To combat this disease, it is crucial to better understand the molecular mechanisms that contribute to its pathogenesis. Herein, we report that apoptosis signal-regulating kinase 1 (ASK1) is(More)
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