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OBJECTIVES The purpose of this study was to investigate whether lavender oil aromatherapy can reduce the bispectral index (BIS) values and stress and decrease the pain of needle insertion in 30 volunteers. SUBJECTS AND METHODS Thirty (30) healthy volunteers were randomly allocated to 2 groups: the experimental group received oxygen with a face mask coated(More)
OBJECTIVE Pain on injection is a well known adverse effect of propofol. The purpose of this study was to compare the analgesic effect of a lidocaine (lignocaine)/remifentanil combination compared with either lidocaine alone or remifentanil alone during propofol injection for induction of anaesthesia. METHODS In a randomised, double-blind, prospective(More)
OBJECTIVES To evaluate the antiemetic efficacy of dexamethasone combined with midazolam after middle ear surgery. STUDY DESIGN A prospective, randomized, double-blind, placebo-controlled study. SETTING University hospital. SUBJECTS AND METHODS The study population consisted of 120 American Society of Anesthesiologists physical status I or II, adult(More)
BACKGROUND Peripheral nerve injury results in chronic neuropathic pain characterized by allodynia and/or spontaneous pain. It has been suggested that activation of mitogen-activated protein kinases such as extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) contribute to the neuropathic pain. OBJECTIVES We investigated if(More)
BACKGROUND Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrinato iron (III) (FeTMPyP) by(More)
BACKGROUND Nausea and vomiting are frequent adverse effects of patient-controlled epidural analgesia (PCEA) with opioids. OBJECTIVE This study was designed to assess the antiemetic effect of midazolam added to fentanyl-ropivacaine PCEA. METHODS In a prospective, randomized, double-blind, controlled trial, smoking patients with gastric cancer undergoing(More)
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