The aim of this study was the development of a geometrically simple and highly computationally-efficient two dimensional (2D) biophysical model of whole heart electrical activity, incorporating spontaneous activation of the sinoatrial node (SAN), the specialized conduction system, and realistic surface ECG morphology computed on the torso. The… (More)
The aim of the study was to develop methodology for long-term study of ECG parameters, in particular the P wave parameters. In this study we address continuous monitoring of different P wave parameters in the group of patients after Coronary Artery Bypass Grafting (CABG) in order to examine potential predictors of atrial fibrillation. Lead II of the… (More)
We present a computationally efficient three-dimensional bidomain model of torso-embedded whole heart electrical activity, with spontaneous initiation of activation in the sinoatrial node, incorporating a specialized conduction system with heterogeneous action potential morphologies throughout the heart. The simplified geometry incorporates the whole heart… (More)
The aim of the study was to develop a multiparameter prediction model of Atrial Fibrillation (AF) after Coronary Artery Bypass Grafting (CABG) based on measured P wave parameters. We recorded the standard II lead ECG for at least 48 hours after surgery in 48 patients. In contrast to previous research and in order to enable the analysis of more data we… (More)
In patients undergoing coronary artery bypass grafting (CABG) surgery, post-operative atrial fibrillation (AF) occurs with a prevalence of up to 40%. The highest incidence is seen between the second and third day after the operation. Following cardiac surgery AF may cause various complications such as hemodynamic instability, heart attack and cerebral or… (More)
This study describes an anatomically realistic 3D bidomain model of whole-heart electrical activity. The heart was embedded in a human torso, incorporating spontaneous activation of the sinoatrial node and including conduction through the specialized conduction pathways with heterogeneous action potential (AP) morphologies throughout the heart. The model… (More)
Active regional conductances and inhomogeneous distribution of membrane ionic channels in dendrites influence the integration of synaptic inputs in cortical neurons. How these properties shape the response properties of retinal ganglion cells (RGC) in the mammalian retina has remained largely unexplored. In this study, we used a morphologically-realistic… (More)
INTRODUCTION The aim of this study is to review existing methods developed for atrial fibrillation (AF) prediction and to analyse the possibility of finding parameters for reliable non-invasive clinical prediction of AF, occurring frequently after Coronary Artery Bypass Grafting (CABG).